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Neoplasm Grading

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C2P-GCN: Cell-to-Patch Graph Convolutional Network for Colorectal Cancer Grading.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Graph-based learning approaches, due to their ability to encode tissue/organ structure information, are increasingly favored for grading colorectal cancer histology images. Recent graph-based techniques involve dividing whole slide images (WSIs) into...

Clinical implications of deep learning based image analysis of whole radical prostatectomy specimens.

Scientific reports
Prostate cancer (PCa) diagnosis faces significant challenges due to its complex pathological characteristics and insufficient pathologist resources. While deep learning-based image analysis (DLIA) shows promise in enhancing diagnostic accuracy, its a...

Deep learning informed multimodal fusion of radiology and pathology to predict outcomes in HPV-associated oropharyngeal squamous cell carcinoma.

EBioMedicine
BACKGROUND: We aim to predict outcomes of human papillomavirus (HPV)-associated oropharyngeal squamous cell carcinoma (OPSCC), a subtype of head and neck cancer characterized with improved clinical outcome and better response to therapy. Pathology an...

Deep learning based on intratumoral heterogeneity predicts histopathologic grade of hepatocellular carcinoma.

BMC cancer
OBJECTIVES: The potential of medical imaging to non-invasively assess intratumoral heterogeneity (ITH) is increasingly being recognized. This study aimed to investigate the value of the ITH-based deep learning model for preoperative prediction of his...

Do explainable AI (XAI) methods improve the acceptance of AI in clinical practice? An evaluation of XAI methods on Gleason grading.

The journal of pathology. Clinical research
This work aimed to evaluate both the usefulness and user acceptance of five gradient-based explainable artificial intelligence (XAI) methods in the use case of a prostate carcinoma clinical decision support system environment. In addition, we aimed t...

Development of Hybrid radiomic Machine learning models for preoperative prediction of meningioma grade on multiparametric MRI.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
PURPOSE: To develop and compare machine learning models for distinguishing low and high grade meningiomas on multiparametric MRI.

Rapid pathologic grading-based diagnosis of esophageal squamous cell carcinoma Raman spectroscopy and a deep learning algorithm.

World journal of gastroenterology
BACKGROUND: Esophageal squamous cell carcinoma is a major histological subtype of esophageal cancer. Many molecular genetic changes are associated with its occurrence. Raman spectroscopy has become a new method for the early diagnosis of tumors becau...

Machine learning-based reconstruction of prognostic staging for gastric cancer patients with different differentiation grades: A multicenter retrospective study.

World journal of gastroenterology
BACKGROUND: The prognosis of gastric cancer (GC) patients is poor, and an accurate prognostic staging system would help assess patients' prognostic status before treatment and determine appropriate treatment strategies.

Artificial intelligence in colorectal cancer liver metastases: From classification to precision medicine.

Bioscience trends
Colorectal cancer liver metastasis (CRLM) remains the leading cause of mortality among colorectal cancer (CRC) patients, with more than half eventually developing hepatic metastases. Achieving long-term survival in CRLM necessitates early detection, ...