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Neoplasm Grading

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Prediction of IDH and TERT promoter mutations in low-grade glioma from magnetic resonance images using a convolutional neural network.

Scientific reports
Identification of genotypes is crucial for treatment of glioma. Here, we developed a method to predict tumor genotypes using a pretrained convolutional neural network (CNN) from magnetic resonance (MR) images and compared the accuracy to that of a di...

One-slice CT image based kernelized radiomics model for the prediction of low/mid-grade and high-grade HNSCC.

Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
An accurate grade prediction can help to appropriate treatment strategy and effective diagnosis to Head and neck squamous cell carcinoma (HNSCC). Radiomics has been studied for the prediction of carcinoma characteristics in medical images. The succes...

Prediction of lower-grade glioma molecular subtypes using deep learning.

Journal of neuro-oncology
INTRODUCTION: It is useful to know the molecular subtype of lower-grade gliomas (LGG) when deciding on a treatment strategy. This study aims to diagnose this preoperatively.

Natural language processing for populating lung cancer clinical research data.

BMC medical informatics and decision making
BACKGROUND: Lung cancer is the second most common cancer for men and women; the wide adoption of electronic health records (EHRs) offers a potential to accelerate cohort-related epidemiological studies using informatics approaches. Since manual extra...

Epithelium segmentation and automated Gleason grading of prostate cancer via deep learning in label-free multiphoton microscopic images.

Journal of biophotonics
In the current clinical care practice, Gleason grading system is one of the most powerful prognostic predictors for prostate cancer (PCa). The grading system is based on the architectural pattern of cancerous epithelium in histological images. Howeve...

Machine Learning Approaches to Radiogenomics of Breast Cancer using Low-Dose Perfusion Computed Tomography: Predicting Prognostic Biomarkers and Molecular Subtypes.

Scientific reports
Radiogenomics investigates the relationship between imaging phenotypes and genetic expression. Breast cancer is a heterogeneous disease that manifests complex genetic changes and various prognosis and treatment response. We investigate the value of m...

Development of a Deep Learning Algorithm for the Histopathologic Diagnosis and Gleason Grading of Prostate Cancer Biopsies: A Pilot Study.

European urology focus
BACKGROUND: The pathologic diagnosis and Gleason grading of prostate cancer are time-consuming, error-prone, and subject to interobserver variability. Machine learning offers opportunities to improve the diagnosis, risk stratification, and prognostic...

Toward Automated Bladder Tumor Stratification Using Confocal Laser Endomicroscopy.

Journal of endourology
Urothelial carcinoma of the bladder (UCB) is the most common urinary cancer. White-light cystoscopy (WLC) forms the corner stone for the diagnosis of UCB. However, histopathological assessment is required for adjuvant treatment selection. Probe-base...