AIMC Topic: Neoplasm Staging
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AI-based multimodal prediction of lymph node metastasis and capsular invasion in cT1N0M0 papillary thyroid carcinoma.
Frontiers in endocrinology
May 27, 2025
BACKGROUND: Accurate preoperative evaluation of cT1N0M0 papillary thyroid carcinoma (PTC) is essential for guiding appropriate treatment strategies. Although ultrasound is widely used for clinical staging, it has limitations in detecting lymph node m...
Integrative analysis of epigenetic and transcriptional interrelations identifies histotype-specific biomarkers in early-stage ovarian carcinoma.
Journal of ovarian research
May 19, 2025
BACKGROUND: Epithelial ovarian cancer (EOC) is a deadly and heterogenous disease comprising five major histotypes: clear cell carcinoma (CCC), endometrioid carcinoma (EC), low- and high-grade serous carcinoma (LGSC, HGSC), and mucinous carcinoma (MC)...
Tumor budding and poorly differentiated clusters as a biological continuum in colorectal cancer invasion and prognosis.
Scientific reports
May 15, 2025
Tumor budding (TB) and poorly differentiated clusters (PDCs) are features of infiltrative growth patterns and powerful independent prognostic factors in colorectal cancer (CRC), yet the underlying biological mechanisms behind their role in CRC invasi...
Exploring the potential of machine learning in gastric cancer: prognostic biomarkers, subtyping, and stratification.
BMC cancer
Apr 30, 2025
BACKGROUND: Advancements in the management of gastric cancer (GC) and innovative therapeutic approaches highlight the significance of the role of biomarkers in GC prognosis. Machine-learning (ML)-based methods can be applied to identify the most impo...
Personalized therapeutic strategies and prognosis for advanced laryngeal squamous cell carcinoma: Insights from machine learning models.
American journal of otolaryngology
Apr 24, 2025
PURPOSE: Despite the development of diverse treatment options, there has been an increase in mortality rates for laryngeal squamous cell carcinoma (LSCC). Our research employed survival analysis and machine learning (ML) techniques to evaluate the im...
A comparative analysis of three graph neural network models for predicting axillary lymph node metastasis in early-stage breast cancer.
Scientific reports
Apr 22, 2025
The presence of axillary lymph node metastasis (ALNM) in breast cancer patients is an important factor in deciding whether to have axillary surgery or pursue alternative treatments. Based on axillary ultrasound (US) and histopathologic data, three gr...
Habitat Radiomics and Deep Learning Features Based on CT for Predicting Lymphovascular Invasion in T1-stage Lung Adenocarcinoma: A Multicenter Study.
Academic radiology
Apr 18, 2025
RATIONALE AND OBJECTIVES: The research aims to examine how CT-derived habitat radiomics can be used to predict lymphovascular invasion (LVI) in patients with T1-stage lung adenocarcinoma (LUAD), and compare its effectiveness to traditional radiomics ...
Updated perspectives on visceral pleural invasion in non-small cell lung cancer: A propensity score-matched analysis of the SEER database.
Current problems in cancer
Apr 18, 2025
BACKGROUND: Visceral pleural invasion (VPI), including PL1 (the tumor invades beyond the elastic layer) and PL2 (the tumor extends to the surface of the visceral pleura), plays a crucial role in staging Non-Small Cell Lung Cancer (NSCLC). However, th...
Comparison of Predictive Performance of Three Lymph Node Staging Systems in Colorectal Signet Ring Cell Carcinoma Based on Machine Learning Model.
Journal of visualized experiments : JoVE
Apr 18, 2025
Lymph node status is a critical prognostic predictor for patients; however, the prognosis of colorectal signet-ring cell carcinoma (SRCC) has garnered limited attention. This study investigates the prognostic predictive capacity of the log odds of po...
Decoding Recurrence in Early-Stage and Locoregionally Advanced Non-Small Cell Lung Cancer: Insights From Electronic Health Records and Natural Language Processing.
JCO clinical cancer informatics
Apr 18, 2025
PURPOSE: Recurrences after curative resection in early-stage and locoregionally advanced non-small cell lung cancer (NSCLC) are common, necessitating a nuanced understanding of associated risk factors. This study aimed to establish a natural language...
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