PURPOSE: This study aims to investigate the impact of tumor quadrant location on the 5-year early-stage breast cancer survivability prediction using explainable machine learning (ML) models. By integrating these predictive models with Shapley Additiv...
International journal of clinical oncology
Mar 17, 2025
BACKGROUND AND PURPOSE: Accurate recurrence risk evaluation in patients with stage II and III colorectal cancer (CRC) remains difficult. Traditional histopathological methods frequently fall short in predicting outcomes after adjuvant chemotherapy. T...
PURPOSE: Existing prognostic staging systems depend on expensive manual extraction by pathologists, potentially overlooking latent patterns critical for prognosis, or use black-box deep learning models, limiting clinical acceptance. This study introd...
BACKGROUND: To evaluate the clinical applicability of deep learning (DL) models based on automatic segmentation in preoperatively predicting tumor spread through air spaces (STAS) in peripheral stage I lung adenocarcinoma (LUAD).
No studies have examined the prognostic value of the log odds of negative lymph nodes/T stage (LONT) in locally advanced rectal cancer (LARC) treated with neoadjuvant chemoradiotherapy (nCRT). We aimed to assess the prognostic value of LONT and devel...
Rectal cancer (RC) is one of the major health challenges worldwide. Accurate staging, restaging, invasiveness assessment, and treatment efficacy evaluation are crucial for its clinical management. Magnetic resonance imaging (MRI) plays a significant ...
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
Feb 25, 2025
BACKGROUND: Evidence is limited on whether patients with advanced pulmonary carcinoid (APC) benefit from comprehensive pulmonary resection (CPR), chemotherapy, or radiotherapy. Existing prognostic models for APC are limited and do not guide treatment...
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
Feb 24, 2025
PURPOSE: This study evaluates a three-dimensional (3D) deep learning (DL) model based on fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) for predicting the preoperative status of spread through air spa...
As non-surgical therapies gain acceptance in head and neck tumors, the importance of imaging has increased. New therapeutic methods (in radiation therapy, targeted biological therapy, immunotherapy) need better tumor characterization and prognostic i...
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
Feb 20, 2025
BACKGROUND: According to current guideline, patients with resected specimens showing high-risk features are recommended additional surgery after local excision (LE) of T1 colorectal cancer, despite the low incidence of recurrence. However, surgical r...
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