The process of protein aggregation, central to neurodegenerative diseases like Huntington's, is challenging to study due to its unpredictable nature and relatively rapid kinetics. Understanding its biomechanics is crucial for unraveling its role in d...
Recent advances in artificial intelligence (AI) have made it possible to detect neurodegenerative diseases (NDDs) earlier, potentially improving patient outcomes. However, AI-based detection tools remain underutilized. We studied individual valuation...
Neurological Disorders (ND) affect a large portion of the global population, impacting the brain, spinal cord, and nerves. These disorders fall into categories such as NeuroDevelopmental (NDD), NeuroBiological (NBD), and NeuroDegenerative (ND) disord...
Recent advances in our understanding of non-cell-autonomous mechanisms in neurodegenerative diseases (NDDs) have highlighted microglial dysfunction as a core driver of disease progression. Conditions such as Alzheimer's disease (AD), amyotrophic late...
Neurodegenerative diseases (NDDs), including Alzheimer's disease (AD) and Parkinson's disease (PD), are a growing global health concern, especially among the elderly, posing significant challenges to well-being and survival. GSK3β, a serine/threonine...
The current depth of site-specific N-glycoproteomics is insufficient to fully characterize glycosylation events in biological samples. Herein, we achieve an ultradeep and precision analysis of the N-glycoproteome of mouse tissues by integrating multi...
INTRODUCTION: Recent research has suggested that neuroinflammation may be important in the pathogenesis of neurodegenerative diseases. Free-water diffusion (FWD) has been proposed as a non-invasive neuroimaging-based biomarker for neuroinflammation.
Signal transduction and targeted therapy
Jun 23, 2025
Traumatic brain injury (TBI) is a major public health concern associated with an increased risk of neurodegenerative diseases including Alzheimer's disease (AD), Parkinson's disease (PD), and chronic traumatic encephalopathy, yet the underlying molec...
Surface-enhanced Raman spectroscopy (SERS) has emerged as a transformative analytical tool in disease diagnostics, offering unparalleled sensitivity and molecular fingerprinting capabilities. However, its clinical translation is hindered by the inher...
In the context of lifestyle changes, stress and other environmental factors have resulted in the sudden hike in dementia globally. This necessitates investigations with respect to every horizon of the due cause for it; further on, the diagnosis and t...
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