BACKGROUND: Epithelial ovarian cancer (EOC) is a deadly and heterogenous disease comprising five major histotypes: clear cell carcinoma (CCC), endometrioid carcinoma (EC), low- and high-grade serous carcinoma (LGSC, HGSC), and mucinous carcinoma (MC)...
BACKGROUND: Ovarian cancer has the highest mortality rate among gynecological cancers, making early detection crucial, as the five-year survival rate drops from 92% with early-stage diagnosis compared to 31% with late-stage diagnosis. Current diagnos...
International journal of surgery (London, England)
May 1, 2025
BACKGROUND: High-grade serous ovarian cancer (HGSOC) remains one of the most challenging gynecological malignancies, with over 70% of ovarian cancer patients ultimately experiencing disease progression. The current prognostic tools for progression-fr...
Conventional ascitic fluid cytology for detecting ovarian cancer is limited by its low sensitivity. To address this issue, this multicenter study developed patch image (PI)-based fully supervised convolutional neural network (CNN) models and clusteri...
We present algorithms for model selection and parameter estimation concerning deleterious genetic mutations. Three models are considered: single gene mutation, double cross-effect mutations or no genetic cause. Each of these models include unknown pa...
Ovarian cancer is associated with high rates of patient mortality and morbidity. Laparoscopic assessment of tumor localization can be used for treatment planning in newly diagnosed high-grade serous ovarian carcinoma (HGSOC). While spread to multiple...
The right classification of variants is the key to pre-symptomatic detection of disease and conducting preventive actions. Since BRCA1 has a high incidence and penetrance in breast and ovarian cancers, a high-performance predictive tool can be employ...
Ovarian cancer surgery requires multiple radical resections with a high risk of complications. The aim of this single-centre, retrospective study was to determine the best method for predicting Clavien-Dindo grade ≥ III complications using machine l...
Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
Apr 9, 2025
Multimodal medical images reveal different characteristics of the same anatomy or lesion, offering significant clinical value. Deep learning has achieved widespread success in medical image analysis with large-scale labeled datasets. However, annotat...
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