INTRODUCTION: Pneumonia is the leading cause of child morbidity and mortality and accounts for 5.6 million under-five child deaths. Pneumonia has a significant impact on the quality of life, the country's economy, and the survival of children. Theref...
There is currently a paucity of research on the effects of early life exposure to particulate matter (PM) of various size fractions on pneumonia in preschool-aged children. We explored the connections between antenatal and postnatal exposure to atmos...
This study investigated and validated all-cause in-hospital death prediction models for hospitalized pneumonia patients based on large-scale clinical data, including diagnoses, medication prescriptions, and laboratory test codes. Feature selection wa...
British journal of clinical pharmacology
Apr 3, 2025
AIMS: The uncertainty about the efficacy and safety of currently used azithromycin dosing regimens in children warrants individualized therapy. The area under the plasma concentration-time curve over 24 h (AUC) of azithromycin correlates best with it...
The American journal of emergency medicine
Mar 27, 2025
BACKGROUND: The rapid advancement of artificial intelligence (AI) has great ability to impact healthcare. Chest X-rays are essential for diagnosing acute thoracic conditions in the emergency department (ED), but interpretation delays due to radiologi...
BACKGROUND: Severe pneumonia has a poor prognosis and high mortality. Current severity scores such as Acute Physiology and Chronic Health Evaluation (APACHE-II) and Sequential Organ Failure Assessment (SOFA), have limited ability to help clinicians i...
Deep Neural Networks (DNN) have achieved state-of-the-art performance in medical image classification and are increasingly being used for disease diagnosis. However, these models are quite complex and that necessitates the need to reduce the model co...
BACKGROUND: Hip fractures have become a significant health concern, particularly among super-aged patients, who were at a high risk of postoperative pneumonia due to their frailty and the presence of multiple comorbidities. This study aims to establi...
PURPOSE: Primary barriers to application of immune checkpoint inhibitor (ICI) therapy for cancer include severe side effects (such as potentially life threatening pneumonitis [PN]), which can cause the discontinuation of treatment. Predicting which p...
BACKGROUND: Severe Community-Acquired Pneumonia (SCAP) is a serious global health issue with high incidence and mortality rates. In recent years, the role of biomarkers such as Connective Tissue Growth Factor (CTGF) and Milk Fat Globule-Epidermal Gro...
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