AIMC Topic: Precision Medicine

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Machine learning-informed liquid-liquid phase separation for personalized breast cancer treatment assessment.

Frontiers in immunology
BACKGROUND: Breast cancer, characterized by its heterogeneity, is a leading cause of mortality among women. The study aims to develop a Machine Learning-Derived Liquid-Liquid Phase Separation (MDLS) model to enhance the prognostic accuracy and person...

Artificial intelligence-based personalized survival prediction using clinical and radiomics features in patients with advanced non-small cell lung cancer.

BMC cancer
BACKGROUND: Multiple first-line treatment options have been developed for advanced non-small cell lung cancer (NSCLC) in each subgroup determined by predictive biomarkers, specifically driver oncogene and programmed cell death ligand-1 (PD-L1) status...

Large Scale Ultrafast Manufacturing of Wireless Soft Bioelectronics Enabled by Autonomous Robot Arm Printing Assisted by a Computer Vision-Enabled Guidance System for Personalized Wound Healing.

Advanced healthcare materials
A Customized wound patch for Advanced tissue Regeneration with Electric field (CARE), featuring an autonomous robot arm printing system guided by a computer vision-enabled guidance system for fast image recognition is introduced. CARE addresses the g...

Artificial intelligence, medications, pharmacogenomics, and ethics.

Pharmacogenomics
Artificial Intelligence (AI) and Machine Learning (ML) are revolutionizing various scientific and clinical disciplines including pharmacogenomics (PGx) by enabling the analysis of complex datasets and the development of predictive models. The integra...

From Images to Genes: Radiogenomics Based on Artificial Intelligence to Achieve Non-Invasive Precision Medicine in Cancer Patients.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
With the increasing demand for precision medicine in cancer patients, radiogenomics emerges as a promising frontier. Radiogenomics is originally defined as a methodology for associating gene expression information from high-throughput technologies wi...

Machine learning for precision diagnostics of autoimmunity.

Scientific reports
Early and accurate diagnosis is crucial to prevent disease development and define therapeutic strategies. Due to predominantly unspecific symptoms, diagnosis of autoimmune diseases (AID) is notoriously challenging. Clinical decision support systems (...

Shareable artificial intelligence to extract cancer outcomes from electronic health records for precision oncology research.

Nature communications
Databases that link molecular data to clinical outcomes can inform precision cancer research into novel prognostic and predictive biomarkers. However, outside of clinical trials, cancer outcomes are typically recorded only in text form within electro...

Personalized cancer vaccine design using AI-powered technologies.

Frontiers in immunology
Immunotherapy has ushered in a new era of cancer treatment, yet cancer remains a leading cause of global mortality. Among various therapeutic strategies, cancer vaccines have shown promise by activating the immune system to specifically target cancer...

Human-Artificial Intelligence Symbiotic Reporting for Theranostic Cancer Care.

Cancer biotherapy & radiopharmaceuticals
Reporting of diagnostic nuclear images in clinical cancer management is generally qualitative. Theranostic treatment with Lu radioligands for prostate cancer and neuroendocrine tumors is routinely given as the same arbitrary fixed administered activi...

Exploring patient stratification in head and neck squamous cell carcinoma using machine learning techniques: Preliminary results.

Current problems in cancer
BACKGROUND: Head and Neck Squamous Cell Carcinoma (HNSCC) presents a significant challenge in oncology due to its inherent heterogeneity. Traditional staging systems, such as TNM (Tumor, Node, Metastasis), provide limited information regarding patien...