AIMC Topic: Precision Medicine

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Current progress of digital twin construction using medical imaging.

Journal of applied clinical medical physics
Medical imaging is fundamental to digital twin technology, enabling patient-specific virtual models of anatomy and physiology. By integrating high-resolution modalities (Magnetic Resonance Imaging (MRI), Computed Tomography (CT), Positron Emission To...

Moving past multidisciplinary discussions and Gender-Age-Physiology model: precision medicine through biological phenotyping in interstitial lung disease.

Current opinion in pulmonary medicine
PURPOSE OF REVIEW: Interstitial lung disease (ILD) presents significant diagnostic and therapeutic challenges due to underlying biological heterogeneity and variable clinical course. Traditional diagnostic and prognostic tools are limited in their ab...

Artificial intelligence and digital twins for the personalised prediction of hypertension risk.

Computers in biology and medicine
Hypertension is a significant global health challenge, contributing substantially to morbidity and mortality through its association with various cardiovascular diseases. Traditional approaches to hypertension risk prediction, which rely on broad epi...

Learning double balancing representation for heterogeneous dose-response curve estimation.

Neural networks : the official journal of the International Neural Network Society
Estimating the individuals' potential response to varying treatment doses is crucial for decision-making in areas such as precision medicine and management science. Most recent studies predict counterfactual outcomes by learning a covariate represent...

The melanoma MEGA-study: Integrating proteogenomics, digital pathology, and AI-analytics for precision oncology.

Journal of proteomics
Melanoma remains the most aggressive form of skin cancer, characterized by high metastatic potential, genetic heterogeneity, and resistance to conventional therapies. The Melanoma MEGA-Study is a multi-center initiative designed to address these clin...

Supporting Personalized prEgnancy Care wIth Artificial inteLligence (SPECIAL): An Acceptability Study of a Personalized Educational Platform.

Studies in health technology and informatics
Postpartum depression (PPD) affects approximately 20% of pregnant individuals, yet half of these cases remain under-treated despite the availability of educational interventions. To address this gap, the Supporting Personalized prEgnancy Care wIth Ar...

Personalized Prediction of Chronic Kidney Disease Progression in Patients with Chronic Kidney Disease Stages 3-5: A Multicenter Study Using the Machine Learning Approach.

Studies in health technology and informatics
Chronic Kidney Disease (CKD) is a prevalent and progressive condition that can lead to end-stage renal disease (ESRD) if left unmanaged. Accurate prediction of CKD progression, particularly in patients with CKD stages 3-5, is essential for early inte...

Preliminary Results from Using Gen-AI to Personalized Medication Leaflets.

Studies in health technology and informatics
The product information of a medicinal product includes the summary of product characteristics (SmPC), package label, and patient information leaflet (PIL), previously available only in paper or pdf format. The European Medicines Agency (EMA) in 2020...