p53 immunohistochemistry (IHC) is widely used as a rapid surrogate for detecting mutations, with mutations being a key biomarker for poor outcomes in lymphomas. We developed two algorithms using digital quantification tools to assess p53 expression...
BACKGROUND: Major depressive disorder (MDD) is characterized by significant heterogeneity in treatment response, with inflammation hypothesized to play a role in its pathophysiology. Peripheral inflammatory biomarkers, such as the neutrophil-to-lymph...
BACKGROUND: Urinary tract infections (UTIs) are among the most common infections encountered in healthcare settings. Current diagnostic practices often require 24-48 h due to the time needed for culture results. Given that 70%-80% of cultures return ...
AIMS: The aim of this research is to diagnose polycythaemia vera (PV) disease using different machine learning (ML) algorithms with complete blood count (CBC) parameters before further investigations such as Janus kinase 2 (), erythropoietin (EPO) an...
OBJECTIVE: In this study, we investigated whether artificial intelligence (AI) analysis of chest radiographs (CXRs) can predict major adverse clinical events in patients visiting the emergency department (ED) with acute cardiopulmonary symptoms.
Liver international : official journal of the International Association for the Study of the Liver
Sep 1, 2025
BACKGROUND AND AIMS: The first variceal haemorrhage (FVH) is a life-threatening complication of liver cirrhosis that requires timely intervention; however, noninvasive tools for accurately predicting FVH remain limited. This study aimed to develop no...
Selection bias has been identified in hypotension prediction models, but its impact on an algorithm's ability to learn relevant information from the arterial waveform remains unclear. The recent study by Yang and colleagues sheds considerable light o...
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
Sep 1, 2025
INTRODUCTION: Mechanical Thrombectomy (MT) is the standard of care in the interventional management of Acute Ischemic Stroke (AIS). The NVQI-QOD registry records detailed patient characteristics, pre-operative imaging, procedure metrics, and post-ope...
INTRODUCTION: Individuals with spinal cord injury (SCI) have varying bladder health trajectories after their injury. We explored whether a predictive machine learning model could identify which variables impact urinary symptoms.
OBJECTIVE: This study aimed to evaluate the diagnostic performance of an artificial intelligence (AI)-based platform (Diagnocat) in detecting periapical radiolucencies (PARLs) in cone-beam computed tomography (CBCT) scans of molars. Specifically, we ...
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