AIMC Topic: Prefrontal Cortex
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Different prefrontal cortex activity patterns in bipolar and unipolar depression during verbal fluency tasks based on functional near infrared spectroscopy study.
Scientific reports
Jul 1, 2025
This study aimed to investigate the functionality of the prefrontal cortex in patients with unipolar depression (UD) and bipolar depression (BD) using functional near-infrared spectroscopy (fNIRS) during a verbal fluency task (VFT). Additionally, it ...
Regional and whole-brain neurofunctional alterations during pain empathic processing of physical but not affective pain in migraine patients.
The journal of headache and pain
Jun 12, 2025
BACKGROUND: Accumulating evidence suggests that migraine patients present abnormal brain responses to salient sensory and emotional stimuli. However, it is still unclear whether this is a generalized or domain-specific phenomenon. Employing a well-va...
Cortical-subcortical neural networks for motor learning and storing sequence memory.
Neural networks : the official journal of the International Neural Network Society
May 7, 2025
Motor sequence learning relies on the synergistic collaboration of multiple brain regions. However, most existing models for motor sequence learning primarily focus on functional-level analyses of sequence memory mechanisms, providing limited neuroph...
An interpretable deep-learning approach to detect biomarkers in anxious-depressed symptoms from prefrontal fNIRS signals during an autobiographical memory test.
Asian journal of psychiatry
Mar 22, 2025
BACKGROUND: Individuals with anxious-depressed (AD) symptoms have more severe mood disorders and cognitive impairment than those with non-anxious depression (NAD) symptoms. Therefore, it is important to clarify the underlying neurophysiology of these...
Effect of Parallel Cognitive-Motor Training Tasks on Hemodynamic Responses in Robot-Assisted Rehabilitation.
Brain connectivity
Feb 20, 2025
Previous studies suggest that the combination of robot-assisted training with other concurrent tasks may promote the functional recovery and improvement better than the single task. It is well-established that robot-assisted rehabilitation training ...
Latent circuit inference from heterogeneous neural responses during cognitive tasks.
Nature neuroscience
Feb 10, 2025
Higher cortical areas carry a wide range of sensory, cognitive and motor signals mixed in heterogeneous responses of single neurons tuned to multiple task variables. Dimensionality reduction methods that rely on correlations between neural activity a...
Random noise promotes slow heterogeneous synaptic dynamics important for robust working memory computation.
Proceedings of the National Academy of Sciences of the United States of America
Jan 16, 2025
Recurrent neural networks (RNNs) based on model neurons that communicate via continuous signals have been widely used to study how cortical neural circuits perform cognitive tasks. Training such networks to perform tasks that require information main...
Brain mapping, biomarker identification and using machine learning method for diagnosis of anxiety during emotional face in preschool children.
Brain research bulletin
Jan 9, 2025
BACKGROUND: Due to the importance and the consequences of anxiety, the goals of the current study are brain mapping, biomarker identification and the use of an assessment method for diagnosis of anxiety during emotional face in preschool children.
Machine Learning Analysis of the Orbitofrontal Cortex Transcriptome of Human Opioid Users Identifies Shisa7 as a Translational Target Relevant for Heroin Seeking Leveraging a Male Rat Model.
Biological psychiatry
Dec 25, 2024
BACKGROUND: Identifying neurobiological targets predictive of the molecular neuropathophysiological signature of human opioid use disorder (OUD) could expedite new treatments. OUD is characterized by dysregulated cognition and goal-directed behavior ...
Accuracy deficits during robotic time-constrained reaching are related to altered prefrontal cortex activity in children with cerebral palsy.
Journal of neuroengineering and rehabilitation
Dec 19, 2024
BACKGROUND: The prefrontal cortex (PFC) is an important node for action planning in the frontoparietal reaching network but its role in reaching in children with cerebral palsy (CP) is unexplored. This case-control study combines a robotic task with ...
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