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Screening of Mangifera indica L. functional content using PCA and neural networks (ANN).

Food chemistry
A method using reversed-phase high-performance liquid chromatography with diode array detection (HPLC-DAD) was applied after extraction with acidified methanol, to determine 12 bioactive phenolic compounds in the peel and pulp of the mango fruit (Man...

Prediction of activation patterns preceding hallucinations in patients with schizophrenia using machine learning with structured sparsity.

Human brain mapping
Despite significant progress in the field, the detection of fMRI signal changes during hallucinatory events remains difficult and time-consuming. This article first proposes a machine-learning algorithm to automatically identify resting-state fMRI pe...

Multiscale High-Level Feature Fusion for Histopathological Image Classification.

Computational and mathematical methods in medicine
Histopathological image classification is one of the most important steps for disease diagnosis. We proposed a method for multiclass histopathological image classification based on deep convolutional neural network referred to as coding network. It c...

Gas chromatography-mass spectrometry metabolomic study of lipopolysaccharides toxicity on rat basophilic leukemia cells.

Chemico-biological interactions
Lipopolysaccharide (LPS) can lead to uncontrollable cytokine production, fatal sepsis syndrome and depression/multiple organ failure, as pathophysiologic demonstration. Various toxic effects of LPS have been extensively reported, mainly on the toxici...

Detection of American Football Head Impacts Using Biomechanical Features and Support Vector Machine Classification.

Scientific reports
Accumulation of head impacts may contribute to acute and long-term brain trauma. Wearable sensors can measure impact exposure, yet current sensors do not have validated impact detection methods for accurate exposure monitoring. Here we demonstrate a ...

Epileptic seizure detection in EEG signal using machine learning techniques.

Australasian physical & engineering sciences in medicine
Epilepsy is a well-known nervous system disorder characterized by seizures. Electroencephalograms (EEGs), which capture brain neural activity, can detect epilepsy. Traditional methods for analyzing an EEG signal for epileptic seizure detection are ti...

Accurate and fast feature selection workflow for high-dimensional omics data.

PloS one
We are moving into the age of 'Big Data' in biomedical research and bioinformatics. This trend could be encapsulated in this simple formula: D = S * F, where the volume of data generated (D) increases in both dimensions: the number of samples (S) and...

In silico toxicity profiling of natural product compound libraries from African flora with anti-malarial and anti-HIV properties.

Computational biology and chemistry
This paper describes an analysis of the diversity and chemical toxicity assessment of three chemical libraries of compounds from African flora (the p-ANAPL, AfroMalariaDb, and Afro-HIV), respectively containing compounds exhibiting activities against...

Derivation of simple rules for complex flow vector fields on the lower part of the human face for robot face design.

Bioinspiration & biomimetics
It is quite difficult for android robots to replicate the numerous and various types of human facial expressions owing to limitations in terms of space, mechanisms, and materials. This situation could be improved with greater knowledge regarding thes...

The neuromorphological caudate-putaminal clustering of neostriate interneurons: Kohonen self-organizing maps and supervised artificial neural networks with multivariate analysis.

Journal of theoretical biology
AIMS: The objective of this study is to investigate the possibility of the neuromorphotopological clustering of neostriate interneurons (NSIN) and their consequent classification into caudate (CIN) and putaminal neuron type (PIN), according to the nu...