Stomach adenocarcinoma (STAD), the most prevalent histological subtype of gastric cancer, exhibits high heterogeneity and poor prognosis, posing significant therapeutic challenges. Parthanatos, a distinct form of regulated cell death mediated by poly...
BACKGROUND: Immunogenic cell death (ICD) triggers antitumor immune responses and plays a critical role in shaping the tumor microenvironment (TME). However, its specific contribution to lung adenocarcinoma (LUAD) progression and immunotherapy respons...
BACKGROUND AND OBJECTIVES: Wilson disease (WD), an inherited copper metabolism disorder, is a cause of acute-on-chronic liver failure (ACLF), posing life-threatening risks due to rapid progression. This study aimed to develop a machine learning (ML)-...
Lymph node metastasis (LNM) is an independent prognostic factor for patients with gastric cancer (GC), and an accurate lymph node (LN) staging system is crucial for guiding adjuvant therapy and assessing patient prognosis. The most commonly used stag...
BACKGROUND: The Coiled-coil domain-containing (CCDC) family, due to its unique protein structural domain and broad involvement in diverse biological processes, has emerged as a focus in oncology research. Nevertheless, its clinical significance and f...
BACKGROUND: Diabetes-related foot ulceration (DFU) is a common complication of diabetes, with a significant impact on survival, health care costs, and health-related quality of life. The prognosis of DFU varies widely among individuals. The Internati...
BACKGROUND: Lymph node metastasis (LNM) is a key prognostic factor in colorectal cancer (CRC), and early lymph node status assessment is crucial for prognosis and immunotherapy decisions. However, the immune characteristics of LNM-negative CRC remain...
Colorectal cancer (CRC) remains a major global health burden with high mortality rates, underscoring the need for effective therapies. This study explores the acetylation characteristics in CRC using single-cell RNA sequencing (scRNA-seq) and weighte...
BACKGROUND: Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is a rare disease with no accurate prognostic tools to predict the prognosis of patients.
BACKGROUND: Classification of risk levels in patients with acute pancreatitis remains a difficult task. Although some biomarkers have emerged to predict the prognosis of patients with acute pancreatitis, they have not been widely used in clinical pra...
Join thousands of healthcare professionals staying informed about the latest AI breakthroughs in medicine. Get curated insights delivered to your inbox.