BACKGROUND: Breast cancer is the most prevalent form of cancer worldwide, with 2.3 million new diagnoses in 2022. Recent advancements in treatment have led to a shift in the use of chemotherapy-targeted immunotherapy from a postoperative adjuvant to ...
Current approaches to estimating cell trajectories, tumor progression dynamics, and cell population diversity of tumor microenvironment often depend on single-cell RNA sequencing, which is costly and resource intensive. To address this limitation, we...
With sepsis remaining a leading cause of mortality, early identification of patients with sepsis and those at high risk of death is a challenge of high socioeconomic importance. Given the potential of hyperspectral imaging (HSI) to monitor microcircu...
Hepatitis B virus (HBV) infection is a major driver of hepatocellular carcinoma (HCC), yet the mechanisms by which HBV triggers HCC and how it interacts with the immune system remain largely undefined. In this study, 53 immune-related key genes invol...
Oral cancer is among the top malignancies and the leading cause of death worldwide. Poor outcomes are attributed to local recurrence and distant metastasis of disease. There is an urgent need to identify the potential biomarkers that may help in prog...
BACKGROUND: Individualized prediction of health outcomes supports clinical medicine and decision making. Our primary objective was to offer a comprehensive survey of methods for the dynamic prediction of Alzheimer's disease (AD), encompassing both co...
BACKGROUND: Parkinson's disease (PD) is a prevalent neurodegenerative condition, the effect of obesity on PD remains controversial. We aimed to investigate the associations of obesity patterns on PD and all-cause mortality, while developing machine l...
INTRODUCTION: Predictive scoring systems support clinicians in decision-making by estimating the prognosis of patients in intensive care units (ICUs). However, there is limited evidence on the accuracy of these systems in predicting mortality and org...
Extracellular vesicles (EVs) exhibit extensive glycosylation modifications, which are promising biomarkers for gastric cancer (GC). However, EV glycomics and the potential application of EV glycosylation patterns in liquid biopsy remain largely unexp...
BACKGROUND: Patients with cancer and cancer survivors often experience multiple chronic health conditions, which can impact symptom burden and treatment outcomes. Despite the high prevalence of multimorbidity, research on cancer prognosis has predomi...
Join thousands of healthcare professionals staying informed about the latest AI breakthroughs in medicine. Get curated insights delivered to your inbox.