Computer methods and programs in biomedicine
Feb 7, 2025
BACKGROUND AND OBJECTIVE: Integrating multimodal data, such as pathology images and genomics, is crucial for understanding cancer heterogeneity, personalized treatment complexity, and enhancing survival prediction. However, most current prognostic me...
RATIONALE AND OBJECTIVES: To develop and validate a computed tomography-based radiomics nomogram for cancer-specific survival (CSS) prediction in curatively resected colorectal cancer (CRC), and its performance was compared with the American Joint Co...
BACKGROUND: Cardiovascular complications are major concerns for Chinese patients with type 2 diabetes. Accurately predicting these risks remains challenging due to limitations in traditional risk models. We aimed to develop a dynamic prediction model...
BACKGROUND: Immunotherapy has introduced new breakthroughs in improving the survival of head and neck squamous cell carcinoma (HNSCC) patients, yet drug resistance remains a critical challenge. Developing personalized treatment strategies based on th...
BACKGROUND: Length of stay (LOS) is a key indicator of posthepatectomy care quality. While clinical factors influencing LOS are identified, the balance between clinical and nonclinical influences remains unquantified. We developed an artificial intel...
Hepatocellular carcinoma (HCC) is the most prevalent and deadly form of liver cancer, and its mortality rate is gradually increasing worldwide. Existing studies used genetic datasets, taken from various platforms, but focused only on common different...
PURPOSE: To investigate the feasibility of characterizing tumor heterogeneity in breast cancer ultrasound images using habitat analysis technology and establish a radiomics machine learning model for predicting response to neoadjuvant chemotherapy (N...
Apoptosis : an international journal on programmed cell death
Feb 4, 2025
The T Cell Receptor (TCR) significantly contributes to tumor immunity, whereas the intricate interplay with the Hepatocellular Carcinoma (HCC) microenvironment and clinical significance remains largely unexplored. Here, we aimed to examine the functi...
BACKGROUND: Tumour vascular density assessed from CD-31 immunohistochemistry (IHC) images has previously been shown to have prognostic value in breast cancer. Current methods to measure vascular density, however, are time-consuming, suffer from high ...
Gastric cancer (GC) is one of the most common tumors; one of the reasons for its poor prognosis is that GC cells can resist normal cell death process and therefore develop distant metastasis. Cuproptosis is a novel type of cell death and a limited nu...
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