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Prognosis

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Machine learning based association between inflammation indicators (NLR, PLR, NPAR, SII, SIRI, and AISI) and all-cause mortality in arthritis patients with hypertension: NHANES 1999-2018.

Frontiers in public health
BACKGROUND: This study aimed to evaluate the relationship between CBC-derived inflammatory markers (NLR, PLR, NPAR, SII, SIRI, and AISI) and all-cause mortality (ACM) risk in arthritis (AR) patients with hypertensive (HTN) using data from the NHANES.

Integrating machine learning models with multi-omics analysis to decipher the prognostic significance of mitotic catastrophe heterogeneity in bladder cancer.

Biology direct
BACKGROUND: Mitotic catastrophe is well-known as a major pathway of endogenous tumor death, but the prognostic significance of its heterogeneity regarding bladder cancer (BLCA) remains unclear.

Machine learning-based identification of cuproptosis-related lncRNA biomarkers in diffuse large B-cell lymphoma.

Cell biology and toxicology
Multiple machine learning techniques were employed to identify key long non-coding RNA (lncRNA) biomarkers associated with cuproptosis in Diffuse Large B-Cell Lymphoma (DLBCL). Data from the TCGA and GEO databases facilitated the identification of 12...

Identification of a telomere-related gene signature for the prognostic and immune landscape prediction in head and neck squamous cell carcinoma by integrated analysis of machine learning and Mendelian randomization.

Medicine
Telomere-related genes (TRGs) are vital in diverse tumor types. Nevertheless, there is a notable lack of in-depth research concerning their significance in head and neck squamous cell carcinoma (HNSCC). In this context, the present study aims to asse...

Protocol of the pilot study to test and evaluate the iCARE tool: a machine learning-based e-platform tool to make health prognoses and support decision-making for the care of older persons with complex chronic conditions.

BMJ open
INTRODUCTION: The provision of optimal care for older adults with complex chronic conditions (CCCs) poses significant challenges due to the interplay of multiple medical, pharmacological, functional and psychosocial factors. To address these challeng...

Identification of gene signatures associated with lactation for predicting prognosis and treatment response in breast cancer patients through machine learning.

Scientific reports
As a newly discovered histone modification, abnormal lactation has been found to be present in and contribute to the development of various cancers. The aim of this study was to investigate the potential role between lactylation and the prognosis of ...

Explainable machine learning for predicting lung metastasis of colorectal cancer.

Scientific reports
Patients with lung metastasis of colorectal cancer typically have a poor prognosis. Therefore, establishing an effective screening and diagnosis model is paramount. Our study seeks to construct and verify a predictive model utilizing machine learning...

Optimizing prediction of metastasis among colorectal cancer patients using machine learning technology.

BMC gastroenterology
BACKGROUND AND AIM: Colorectal cancer is among the most prevalent and deadliest cancers. Early prediction of metastasis in patients with colorectal cancer is crucial in preventing it from the advanced stages and enhancing the prognosis among these pa...

Predicting mortality and risk factors of sepsis related ARDS using machine learning models.

Scientific reports
Sepsis related acute respiratory distress syndrome (ARDS) is a common and serious disease in clinic. Accurate prediction of in-hospital mortality of patients is crucial to optimize treatment and improve prognosis under the new global definition of AR...

Decoding Recurrence in Early-Stage and Locoregionally Advanced Non-Small Cell Lung Cancer: Insights From Electronic Health Records and Natural Language Processing.

JCO clinical cancer informatics
PURPOSE: Recurrences after curative resection in early-stage and locoregionally advanced non-small cell lung cancer (NSCLC) are common, necessitating a nuanced understanding of associated risk factors. This study aimed to establish a natural language...