AIMC Topic: Rats, Sprague-Dawley
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Regeneration of Denervated Skeletal Muscles - Brunelli's CNS-PNS Paradigm.
Journal of medicine and life
Jan 1, 2019
The restoration of voluntary muscle activity in posttraumatic paraplegia in both animal experiments and other clinical applications requires reproducibility of a technically-demanding microsurgical procedure, limited by physicians' understanding of B...
Metabonomics of d-glucaro-1,4-lactone in preventing diethylnitrosamine-induced liver cancer in rats.
Pharmaceutical biology
Dec 1, 2018
CONTEXT: d-Glucaro-1,4-lactone (1,4-GL) exists in many vegetables and fruits. Metabonomics has not been used to investigate the role of 1,4-GL in preventing liver cancer.
Mangosteen ethanol extract alleviated the severity of collagen-induced arthritis in rats and produced synergistic effects with methotrexate.
Pharmaceutical biology
Dec 1, 2018
CONTEXT: Garcinia mangostana Linn. (Guttiferae) pericarp is used as a traditional medicine in South Asia to treat inflammatory diseases.
Evaluation of the potential nephrotoxicity and mechanism in rats after long-term exposure to the traditional Tibetan medicine tsothel.
Pharmaceutical biology
Dec 1, 2018
CONTEXT: Tsothel, a traditional Tibetan medicine, is regarded as 'the king of essences'. Nevertheless, tsothel has aroused serious concern regarding its biosafety because its main component is HgS. Unfortunately, toxicological studies on tsothel are ...
Effect of simvastatin on the SIRT2/NF-κB pathway in rats with acute pulmonary embolism.
Pharmaceutical biology
Dec 1, 2018
CONTEXT: Statins have been widely used in acute pulmonary embolism (APE), while simvastatin has been well-established for the prevention of pulmonary hypertension, which was supposed to be an attractive recommendation for APE treatment.
Anti-hepatofibrosis effect of Allium senescens in activated hepatic stellate cells and thioacetamide-induced fibrosis rat model.
Pharmaceutical biology
Dec 1, 2018
CONTEXT: Allium senescens Linn. (Liliaceae) (ASL) has been traditionally used in Korea and other Asian countries for improving digestive and liver functions.
[rhPDGF-BB promotes migration of bone marrow stromal stem cells in diabetic rats].
Shanghai kou qiang yi xue = Shanghai journal of stomatology
Dec 1, 2018
PURPOSE: To evaluate the effect of different concentrations of rhPDGF-BB on bone marrow stromal stem cells(BMSCs) migration in diabetic rat, and related mechanisms of SDF-1 and its G-protein conjugated receptor regulation, provide a theoretical basis...
[Effects of treatment on ultrastructure of olfactory bulb and GFAP expression in mice with Parkinson's disease].
Zhongguo zhen jiu = Chinese acupuncture & moxibustion
Oct 12, 2018
OBJECTIVE: To observe the effects of treatment on the ultrastructure of olfactory bulb and the expression of substantia nigra glial fibrillary acidic protein (GFAP) in mice with Parkinson's disease (PD) induced by lipopolysaccharide (LPS), and to pr...
[Experimental study of a new animal model with trigeminal neuralgia produced by administration of talc to peripheral infraobital nerve in rats].
Shanghai kou qiang yi xue = Shanghai journal of stomatology
Oct 1, 2018
PURPOSE: To establish a new animal model of trigeminal neuralgia（TN） produced by administration of talc to peripheral infraobital nerve in rats.
[Acupoint injection of BMSCs combined with Chinese herbs for capillary density in ischemic hind limb of diabetes mellitus rats].
Zhongguo zhen jiu = Chinese acupuncture & moxibustion
Sep 12, 2018
OBJECTIVE: To observe the effect of acupoint injection of bone mesenchymal stem cells (BMSCs) combined with Chinese herbs of benefiting for activating blood circulation for capillary density and arterioles density in skeletal muscle in ischemic hind...
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