AIMC Topic: Rats
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Quantitative Assessment of Epithelial Proliferation in Rat Mammary Gland Using Artificial Intelligence Independent of Choice of Proliferation Marker.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society
Jan 20, 2022
Epithelial proliferation in the rat mammary gland is recommended in regulatory guidelines as an endpoint for assessment of the in vivo carcinogenic potential of insulin analogues. Epithelial proliferation is traditionally assessed by immunohistochemi...
The Anti-Adiposity Mechanisms of Ampelopsin and Vine Tea Extract in High Fat Diet and Alcohol-Induced Fatty Liver Mouse Models.
Molecules (Basel, Switzerland)
Jan 18, 2022
(AG) is an ancient medicinal plant that is mainly distributed and used in southwest China. It exerts therapeutic effects, such as antioxidant, anti-diabetic, and anti-inflammatory activities, reductions in blood pressure and cholesterol and hepatopr...
A simultaneous multi-slice T mapping framework based on overlapping-echo detachment planar imaging and deep learning reconstruction.
Magnetic resonance in medicine
Jan 11, 2022
PURPOSE: Quantitative MRI (qMRI) is of great importance to clinical medicine and scientific research. However, most qMRI techniques are time-consuming and sensitive to motion, especially when a large 3D volume is imaged. To accelerate the acquisition...
Metaheuristics with Deep Learning-Enabled Parkinson's Disease Diagnosis and Classification Model.
Journal of healthcare engineering
Jan 10, 2022
Parkinson's disease (PD) affects the movement of people, including the differences in writing skill, speech, tremor, and stiffness in muscles. It is significant to detect the PD at the initial stages so that the person can live a peaceful life for a ...
Gibberellic acid-induced hepatorenal dysfunction and oxidative stress: Mitigation by quercetin through modulation of antioxidant, anti-inflammatory, and antiapoptotic activities.
Journal of food biochemistry
Jan 5, 2022
The plant growth regulator gibberellic acid (GA3) is widely used in agriculture in many countries. However, little is known about its danger to human health or its physiologic and biochemical pathways. Our study examined the effect of GA3 on liver an...
Contribution of phosphorus and PTH to the development of cardiac hypertrophy and fibrosis in an experimental model of chronic renal failure.
Nefrologia
Jan 3, 2022
BACKGROUND AND OBJECTIVE: Adequate serum phosphorus levels in patients with chronic kidney disease is essential for their clinical management. However, the control of hyperphosphatemia is difficult because is normally associated with increases in ser...
Aquoeus Extracts of Daucus Carota (Linn) Protected the Postnatal Developing Cerebellum of Wistar Rats Against Arsenic-Induced Oxidative Stress.
Nigerian journal of physiological sciences : official publication of the Physiological Society of Nigeria
Dec 31, 2021
The neuroprotective effects of the aqueous extract of Daucus carota (Dc) tuber against arsenic-induced oxidative damage on the developing cerebellum of Wistar rats were studied. Twenty-five pregnant rats (110-200g) were divided into five groups (n=5)...
Modeling CRISPR gene drives for suppression of invasive rodents using a supervised machine learning framework.
PLoS computational biology
Dec 29, 2021
Invasive rodent populations pose a threat to biodiversity across the globe. When confronted with these invaders, native species that evolved independently are often defenseless. CRISPR gene drive systems could provide a solution to this problem by sp...
Pharmacokinetics of panduratin A following oral administration of a Boesenbergia pandurata extract to rats.
Journal of food and drug analysis
Dec 15, 2021
Boesenbergia pandurata and its major active ingredient, panduratin A (PAN), exhibit antibacterial, anti-oxidant, anti-inflammatory, and anti-obesity effects. We explored the time course of the plasma and tissue (in the major organs, gums and skin) co...
Implementation and Practice of Deep Learning-Based Instance Segmentation Algorithm for Quantification of Hepatic Fibrosis at Whole Slide Level in Sprague-Dawley Rats.
Toxicologic pathology
Dec 5, 2021
Exponential development in artificial intelligence or deep learning technology has resulted in more trials to systematically determine the pathological diagnoses using whole slide images (WSIs) in clinical and nonclinical studies. In this study, we a...
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