Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
40039599
Electroceutical methodologies utilized for treating neurological disorders, including stroke, can leverage neuromorphic engineering principles to design devices capable of seamlessly interfacing with the neural system. This paper introduces a bank of...
Cell transplantation is a promising approach for addressing neurodegenerative conditions. In this study, we developed a robot-assisted stereotactic microinjection system for transplanting cells. We evaluated the factors that affect cellular graft via...
International journal of medical sciences
40027191
Rat models are widely used to study cataracts due to their cost-effectiveness and prominent physiological and genetic similarities to humans The objective of this study was to identify genes involved in cataractogenesis due to galactose exposure in ...
BACKGROUND: Neuropathic pain (NP) can be induced by a variety of clinical conditions, such as spinal cord injury, lumbar disc herniation (LDH), lumbar spinal stenosis, diabetes, herpes zoster, and spinal cord tumors, and inflammatory stimuli. The pat...
High-density probes allow electrophysiological recordings from many neurons simultaneously across entire brain circuits but fail to reveal cell type. Here, we develop a strategy to identify cell types from extracellular recordings in awake animals an...
Contrast-enhanced UTE-MRA provides detailed angiographic information but at the cost of prolonged scanning periods, which may impose moving artifacts and affect the promptness of diagnosis and treatment of time-sensitive diseases like stroke. This st...
A successful drug needs to combine several properties including high potency and good pharmacokinetic (PK) properties to sustain efficacious plasma concentration over time. To estimate required doses for preclinical animal efficacy models or for the ...
BACKGROUND: Within the past two decades, high-profile cases of melamine (MA) exposure have raised significant toxicological concerns, particularly regarding food adulteration. While widely used as a fundamental organic chemical intermediate in variou...
Journal of chemical information and modeling
40084909
Ischemic stroke's complex pathophysiology demands therapeutic approaches targeting multiple pathways simultaneously, yet current treatments remain limited. We developed an innovative drug discovery pipeline combining a deep learning approach with exp...
Journal of the experimental analysis of behavior
40072340
Robots are increasingly used alongside Skinner boxes to train animals in operant conditioning tasks. Similarly, animals are being employed in artificial intelligence research to train various algorithms. However, both types of experiments rely on uni...