Journal of cardiothoracic and vascular anesthesia
Dec 2, 2016
OBJECTIVE: Acute hyperglycemia causes endothelial dysfunction in diabetic patients, abolishes ischemic pre- and postconditioning, and is an independent predictor of adverse outcome after myocardial infarction in nondiabetic patients. Its effects on e...
BACKGROUND: Ischemia-reperfusion injury (IRI) is closely associated with numerous severe postoperative complications, including acute rejection, delayed graft function (DGF) and graft failure. Macrophages are central to modulating the aseptic inflamm...
Patients with metabolic dysfunction-associated steatotic liver disease (MASLD) are more susceptible to liver ischemia-reperfusion injury (LIRI), complicating liver surgery outcomes. This study aimed to uncover shared hub genes and mechanisms linking ...
BACKGROUND: While liver transplantation saves lives from irreversible liver damage, it poses challenges such as graft dysfunction due to factors like ischemia-reperfusion (IR) injury, which can lead to significant cellular damage and systemic complic...
AIM OF THE STUDY: To establish a cross-tissue bioinformatics model for identifying conserved key genes and immune infiltration mechanisms in ischemia-reperfusion injury (IRI) with experimental validation in limb IRI, including pharmacological targeti...
Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition
Sep 1, 2016
OBJECTIVES: To investigate the protective effect of Tanshinone IIA (TSA) on oxygen-glucose deprivation and reperfusion (OGD/R) injury of BV-2 cell and its NLRP3 inflammatory signaling pathway.
Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi
Dec 1, 2015
This study demonstrates that nerve growth factor (NGF) plays a protective role in myocardial infarction and early reperfusion by reducing the myocardial cell apoptosis and by improving ventricular remodeling and seeks to assess the effects and mechan...
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
Oct 1, 2015
OBJECTIVE: To investigate the mechanism of Musk and Borneol on cerebral ischemia and reperfusion injury at different time points of acute phase in rats.
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