AIMC Topic: ROC Curve

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Automated Identification of Diabetic Retinopathy Using Deep Learning.

Ophthalmology Mar 27, 2017
PURPOSE: Diabetic retinopathy (DR) is one of the leading causes of preventable blindness globally. Performing retinal screening examinations on all diabetic patients is an unmet need, and there are many undiagnosed and untreated cases of DR. The obje...
Humans Diabetic Retinopathy Neural Networks, Computer Image Interpretation, Computer-Assisted Diagnostic Techniques, Ophthalmological Ophthalmologists Machine Learning Algorithms Reproducibility of Results ROC Curve
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A multi-resolution approach for spinal metastasis detection using deep Siamese neural networks.

Computers in biology and medicine Mar 27, 2017
Spinal metastasis, a metastatic cancer of the spine, is the most common malignant disease in the spine. In this study, we investigate the feasibility of automated spinal metastasis detection in magnetic resonance imaging (MRI) by using deep learning ...
Humans Neural Networks, Computer Female ROC Curve Aged Magnetic Resonance Imaging Image Interpretation, Computer-Assisted Male Spinal Neoplasms Middle Aged
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Utilization of machine learning for prediction of post-traumatic stress: a re-examination of cortisol in the prediction and pathways to non-remitting PTSD.

Translational psychiatry Mar 21, 2017
To date, studies of biological risk factors have revealed inconsistent relationships with subsequent post-traumatic stress disorder (PTSD). The inconsistent signal may reflect the use of data analytic tools that are ill equipped for modeling the comp...
Lymphocytes Heart Rate Adrenocorticotropic Hormone Linear Models Urine Wounds and Injuries Psychological Trauma Receptors, Glucocorticoid Emergency Service, Hospital Norepinephrine Hydrocortisone Saliva Support Vector Machine Longitudinal Studies Blood Pressure Area Under Curve Machine Learning Algorithms Risk Assessment Female Humans Adult Stress Disorders, Post-Traumatic Young Adult ROC Curve Male
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Machine-learning algorithms define pathogen-specific local immune fingerprints in peritoneal dialysis patients with bacterial infections.

Kidney international Mar 17, 2017
The immune system has evolved to sense invading pathogens, control infection, and restore tissue integrity. Despite symptomatic variability in patients, unequivocal evidence that an individual's immune system distinguishes between different organisms...
Reproducibility of Results Aged Aged, 80 and over Young Adult Humans Machine Learning Biomarkers Female Case-Control Studies Adolescent Time Factors ROC Curve Bacteria Adult Male Point-of-Care Systems Middle Aged Gram-Negative Bacterial Infections Peptide Mapping Peritonitis Peritoneal Dialysis Nonlinear Dynamics Pattern Recognition, Automated Host-Pathogen Interactions Gram-Positive Bacterial Infections Predictive Value of Tests Area Under Curve Acute Disease Point-of-Care Testing
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Shared Consensus Machine Learning Models for Predicting Blood Stage Malaria Inhibition.

Journal of chemical information and modeling Mar 17, 2017
The development of new antimalarial therapies is essential, and lowering the barrier of entry for the screening and discovery of new lead compound classes can spur drug development at organizations that may not have large compound screening libraries...
Models, Theoretical Bayes Theorem Machine Learning Malaria Temperature Drug Discovery Antimalarials ROC Curve Quantitative Structure-Activity Relationship
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Generating highly accurate prediction hypotheses through collaborative ensemble learning.

Scientific reports Mar 17, 2017
Ensemble generation is a natural and convenient way of achieving better generalization performance of learning algorithms by gathering their predictive capabilities. Here, we nurture the idea of ensemble-based learning by combining bagging and boosti...
Area Under Curve Numerical Analysis, Computer-Assisted Machine Learning Algorithms ROC Curve Models, Theoretical
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Prediction of virus-host infectious association by supervised learning methods.

BMC bioinformatics Mar 14, 2017
BACKGROUND: The study of virus-host infectious association is important for understanding the functions and dynamics of microbial communities. Both cellular and fractionated viral metagenomic data generate a large number of viral contigs with missing...
Metagenomics Host-Pathogen Interactions Genome, Viral Likelihood Functions Viruses Reproducibility of Results Support Vector Machine DNA, Viral Sequence Analysis, DNA Bayes Theorem ROC Curve Bacteria Logistic Models Models, Theoretical
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GFD-Net: A novel semantic similarity methodology for the analysis of gene networks.

Journal of biomedical informatics Mar 6, 2017
Since the popularization of biological network inference methods, it has become crucial to create methods to validate the resulting models. Here we present GFD-Net, the first methodology that applies the concept of semantic similarity to gene network...
ROC Curve Gene Regulatory Networks Semantics Gene Ontology Humans Algorithms
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Leveraging electronic health records for predictive modeling of post-surgical complications.

Statistical methods in medical research Mar 1, 2017
Hospital-specific electronic health record systems are used to inform clinical practice about best practices and quality improvements. Many surgical centers have developed deterministic clinical decision rules to discover adverse events (e.g. postope...
Regression Analysis Clinical Decision-Making Humans Risk Assessment Machine Learning Postoperative Complications Algorithms ROC Curve Electronic Health Records
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Study of Structure-active Relationship for Inhibitors of HIV-1 Integrase LEDGF/p75 Interaction by Machine Learning Methods.

Molecular informatics Feb 28, 2017
HIV-1 integrase (IN) is a promising target for anti-AIDS therapy, and LEDGF/p75 is proved to enhance the HIV-1 integrase strand transfer activity in vitro. Blocking the interaction between IN and LEDGF/p75 is an effective way to inhibit HIV replicati...
Molecular Conformation Humans HIV Integrase Reproducibility of Results Models, Molecular Molecular Structure Intercellular Signaling Peptides and Proteins ROC Curve HIV Integrase Inhibitors Machine Learning Protein Binding Computer Simulation Structure-Activity Relationship
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