Sarcomas are malignant soft tissue and bone tumours affecting adults, adolescents and children. They represent a morphologically heterogeneous class of tumours and some entities lack defining histopathological features. Therefore, the diagnosis of sa...
Although genome-wide DNA methylomes have demonstrated their clinical value as reliable biomarkers for tumor detection, subtyping, and classification, their direct biological impacts at the individual gene level remain elusive. Here we present Methyla...
Intensity harmonization techniques (IHT) are mandatory to homogenize multicentric MRIs before any quantitative analysis because signal intensities (SI) do not have standardized units. Radiomics combine quantification of tumors' radiological phenotype...
AJR. American journal of roentgenology
Jul 29, 2020
The purpose of this study was to assess the value of radiomics features for differentiating soft tissue sarcomas (STSs) of different histopathologic grades. The T1-weighted and fat-suppressed T2-weighted MR images of 70 STSs of varying grades (35 l...
Computer methods and programs in biomedicine
Nov 13, 2019
Computer aided diagnostic (CAD) has become a significant tool in expanding patient quality-of-life by reducing human errors in diagnosis. CAD can expedite decision-making on complex clinical data automatically. Since brain diseases can be fatal, rapi...
AIM: To realise the automated prediction of soft-tissue sarcoma (STS) grading and lung metastasis based on computed tomography (CT), T1-weighted (T1W) magnetic resonance imaging (MRI), and fat-suppressed T2-weighted MRI (FST2W) via the convolutional ...
Based on morphology it is often challenging to distinguish between the many different soft tissue sarcoma subtypes. Moreover, outcome of disease is highly variable even between patients with the same disease. Machine learning on transcriptome sequenc...
RATIONALE AND OBJECTIVE: Uterine leiomyomas with high signal intensity on T2-weighted imaging (T2WI) can be difficult to distinguish from sarcomas. This study assessed the feasibility of using machine learning to differentiate uterine sarcomas from l...
PURPOSE: To propose a computer-assisted method for distinguishing uterine sarcoma from leiomyomas based on perfusion weighted magnetic resonance imaging (PWI).
The aim of this report is to unveil specific prognostic factors for retroperitoneal sarcoma (RPS) patients by univariate and multivariate statistical techniques. A phase I-II study on localized RPS treated with high-dose ifosfamide and radiotherapy f...
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