AIMC Topic: Sensitivity and Specificity

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The utility of sentinel lymph node mapping in the management of endometrial atypical hyperplasia.

Gynecologic oncology Dec 28, 2017
OBJECTIVES: To determine the risk of endometrial cancer (EC) and lymph node involvement in patients with a preoperative diagnosis of "AH-only" versus "AH - cannot rule out carcinoma" and to study the value of SLN mapping.
Humans Female Aged Carcinoma, Endometrioid Endometrial Hyperplasia Lymphatic Metastasis Myometrium Sentinel Lymph Node Biopsy Neoplasm Invasiveness Lymph Node Excision Neoplasm Grading Predictive Value of Tests Aged, 80 and over Pelvis Neoplasm Staging Adult Endometrial Neoplasms Sensitivity and Specificity CA-125 Antigen Middle Aged Membrane Proteins
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High-sensitivity direct analysis of aflatoxins in peanuts and cereal matrices by ultra-performance liquid chromatography with fluorescence detection involving a large volume flow cell.

Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes Dec 26, 2017
This paper reports a sensitive and cost effective method of analysis for aflatoxins B1, B2, G1 and G2. The sample preparation method was primarily optimised in peanuts, followed by its validation in a range of peanut-processed products and cereal (ri...
Chromatography, High Pressure Liquid Arachis Aflatoxins Aspergillus flavus Food Analysis Food Microbiology Limit of Detection Edible Grain Reproducibility of Results Sensitivity and Specificity Fluorescence Food Contamination
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Characteristics Associated With Decreased or Increased Mortality Risk From Glycemic Therapy Among Patients With Type 2 Diabetes and High Cardiovascular Risk: Machine Learning Analysis of the ACCORD Trial.

Diabetes care Dec 26, 2017
OBJECTIVE: Identifying patients who may experience decreased or increased mortality risk from intensive glycemic therapy for type 2 diabetes remains an important clinical challenge. We sought to identify characteristics of patients at high cardiovasc...
Humans Machine Learning Body Mass Index Biomarkers Follow-Up Studies Sample Size Double-Blind Method Glycated Hemoglobin Cardiovascular Diseases Middle Aged Risk Factors Blood Glucose Diabetes Mellitus, Type 2 Aged Treatment Outcome Adult Sensitivity and Specificity
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Ultrasound Characterization of Bone Demineralization Using a Support Vector Machine.

Ultrasound in medicine & biology Dec 25, 2017
We propose an ultrasound-guided remote measurement technique, utilizing an acoustic radiation force beam as our excitation source and a receiving hydrophone, to assess non-invasively a bone's mechanical properties. Features, such as velocity, were ex...
Reproducibility of Results Rabbits Bone and Bones Phantoms, Imaging Elasticity Imaging Techniques Bone Demineralization, Pathologic Sensitivity and Specificity Animals Image Processing, Computer-Assisted Support Vector Machine Disease Models, Animal
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Artificial intelligence may help in predicting the need for additional surgery after endoscopic resection of T1 colorectal cancer.

Endoscopy Dec 22, 2017
BACKGROUND AND STUDY AIMS: Decisions concerning additional surgery after endoscopic resection of T1 colorectal cancer (CRC) are difficult because preoperative prediction of lymph node metastasis (LNM) is problematic. We investigated whether artificia...
Middle Aged Risk Assessment Models, Theoretical Lymphatic Metastasis Neoplasm Staging Endoscopy Heuristics Artificial Intelligence Sensitivity and Specificity Japan Colorectal Neoplasms Humans Unnecessary Procedures Diagnostic Errors Male Prognosis Female Aged
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Prognostic Implications of Magnetic Resonance-Derived Quantification in Asymptomatic Patients With Organic Mitral Regurgitation: Comparison With Doppler Echocardiography-Derived Integrative Approach.

Circulation Dec 21, 2017
BACKGROUND: Magnetic resonance imaging (MRI) is an accurate method for the quantitative assessment of organic mitral regurgitation (OMR). The aim of the present study was to compare the discriminative power of MRI quantification and the recommended D...
Sensitivity and Specificity Male Middle Aged Severity of Illness Index ROC Curve Prognosis Female Reproducibility of Results Aged Kaplan-Meier Estimate Echocardiography, Doppler Magnetic Resonance Imaging Area Under Curve Mitral Valve Mitral Valve Insufficiency Proportional Hazards Models Humans
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Diagnostic utility of serum melatonin levels in systemic lupus erythematosus: a case-control study.

Reumatismo Dec 21, 2017
Systemic lupus erythematosus (SLE) is a chronic systemic autoimmune inflammatory disease and early diagnosis is of clinical and therapeutic importance. Melatonin is an endogenous endolamine hormone that plays an important role in the immune system du...
Lupus Erythematosus, Systemic Melatonin Humans Male Biomarkers Case-Control Studies Female Immunosuppressive Agents Young Adult Predictive Value of Tests Adult Sensitivity and Specificity
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Enhancing interpretability of automatically extracted machine learning features: application to a RBM-Random Forest system on brain lesion segmentation.

Medical image analysis Dec 20, 2017
Machine learning systems are achieving better performances at the cost of becoming increasingly complex. However, because of that, they become less interpretable, which may cause some distrust by the end-user of the system. This is especially importa...
Machine Learning Algorithms Reproducibility of Results Sensitivity and Specificity Brain Neoplasms Magnetic Resonance Imaging Stroke Image Interpretation, Computer-Assisted Humans
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An algorithm for the classification of mRNA patterns in eosinophilic esophagitis: Integration of machine learning.

The Journal of allergy and clinical immunology Dec 19, 2017
BACKGROUND: Diagnostic evaluation of eosinophilic esophagitis (EoE) remains difficult, particularly the assessment of the patient's allergic status.
Child Decision Support Systems, Clinical Humans RNA, Messenger Sensitivity and Specificity Factor Analysis, Statistical Machine Learning Registries Male Algorithms Eosinophilic Esophagitis Single-Blind Method Decision Support Techniques Infant Genetic Markers Adolescent Female Immunohistochemistry Child, Preschool
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A European multicenter study on the analytical performance of the VERIS HBV assay.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology Dec 19, 2017
BACKGROUND: Hepatitis B viral load monitoring is an essential part of managing patients with chronic Hepatits B infection. Beckman Coulter has developed the VERIS HBV Assay for use on the fully automated Beckman Coulter DxN VERIS Molecular Diagnostic...
Europe Real-Time Polymerase Chain Reaction Limit of Detection Humans Hepatitis B virus RNA, Viral Automation, Laboratory Hepatitis B Sensitivity and Specificity Genotype Viral Load Molecular Diagnostic Techniques
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