AIMC Topic: Severity of Illness Index

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Machine learning-based prediction of radiographic progression in patients with axial spondyloarthritis.

Clinical rheumatology
INTRODUCTION: Machine learning is applied to characterize the risk and predict outcomes in multi-dimensional data. The prediction of radiographic progression in axial spondyloarthritis (axSpA) remains limited. Hence, we tested the feasibility of supe...

The hidden information in patient-reported outcomes and clinician-assessed outcomes: multiple sclerosis as a proof of concept of a machine learning approach.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
Machine learning (ML) applied to patient-reported (PROs) and clinical-assessed outcomes (CAOs) could favour a more predictive and personalized medicine. Our aim was to confirm the important role of applying ML to PROs and CAOs of people with relapsin...

Impact of age at onset on the phenomenology of depression in treatment-seeking adults in the STAR*D trial.

Journal of affective disorders
BACKGROUND: - Adolescence is characterized by biological, emotional, and behavioral changes. The onset of depression during this vulnerable time may confer specific risks. This study examined whether symptoms of depression were associated with age at...

Analysis of substance use and its outcomes by machine learning I. Childhood evaluation of liability to substance use disorder.

Drug and alcohol dependence
BACKGROUND: Substance use disorder (SUD) exacts enormous societal costs in the United States, and it is important to detect high-risk youths for prevention. Machine learning (ML) is the method to find patterns and make prediction from data. We hypoth...

CNN-based diagnosis models for canine ulcerative keratitis.

Scientific reports
The purpose of this methodological study was to develop a convolutional neural network (CNN), which is a recently developed deep-learning-based image recognition method, to determine corneal ulcer severity in dogs. The CNN model was trained with imag...

Analysis of substance use and its outcomes by machine learning: II. Derivation and prediction of the trajectory of substance use severity.

Drug and alcohol dependence
BACKGROUND: This longitudinal study explored the utility of machine learning (ML) methodology in predicting the trajectory of severity of substance use from childhood to thirty years of age using a set of psychological and health characteristics.

Development and accuracy of an artificial intelligence algorithm for acne grading from smartphone photographs.

Experimental dermatology
We developed an artificial intelligence algorithm (AIA) for smartphones to determine the severity of facial acne using the GEA scale and to identify different types of acne lesion (comedonal, inflammatory) and postinflammatory hyperpigmentation (PIHP...

Machine Learning to Understand the Immune-Inflammatory Pathways in Fibromyalgia.

International journal of molecular sciences
Fibromyalgia (FM) is a chronic syndrome characterized by widespread musculoskeletal pain, and physical and emotional symptoms. Although its pathophysiology is largely unknown, immune-inflammatory pathways may be involved. We examined serum interleuki...