AIMC Topic: Tissue Scaffolds
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Predicting degradation rate of genipin cross-linked gelatin scaffolds with machine learning.
Materials science & engineering. C, Materials for biological applications
Oct 24, 2019
Genipin can improve weak mechanical properties and control high degradation rate of gelatin, as a cross-linker of gelatin which is widely used in tissue engineering. In this study, genipin cross-linked gelatin biodegradable porous scaffolds with diff...
Applications of Computer Modeling and Simulation in Cartilage Tissue Engineering.
Tissue engineering and regenerative medicine
Oct 5, 2019
BACKGROUND: Advances in cartilage tissue engineering have demonstrated noteworthy potential for developing cartilage for implantation onto sites impacted by joint degeneration and injury. To supplement resource-intensive in vivo and in vitro studies ...
Simvastatin and nanofibrous poly(l-lactic acid) scaffolds to promote the odontogenic potential of dental pulp cells in an inflammatory environment.
Acta biomaterialia
Dec 30, 2017
UNLABELLED: In this study, we investigated the anti-inflammatory, odontogenic and pro-angiogenic effects of integrating simvastatin and nanofibrous poly(l-lactic acid) (NF-PLLA) scaffolds on dental pulp cells (DPCs). Highly porous NF-PLLA scaffolds t...
Cell Differentiation
Human Umbilical Vein Endothelial Cells
Alkaline Phosphatase
Mesenchymal Stem Cells
Signal Transduction
Lipopolysaccharides
Dental Pulp
Simvastatin
Neovascularization, Physiologic
Biomarkers
Cytoprotection
Polyesters
Young Adult
Humans
Nanofibers
Gene Expression Regulation
RNA, Messenger
Tissue Scaffolds
Odontogenesis
Inflammation
Biodegradable microrobots for targeting cell delivery.
Medical hypotheses
Feb 28, 2017
These days, cell delivery is considered a potential method for treatment of many genetic diseases or tissue regeneration applications. In conventional cell delivery methods, cells are encapsulated in or cultured on biocompatible polymers. However, th...
Controlled surface morphology and hydrophilicity of polycaprolactone toward human retinal pigment epithelium cells.
Materials science & engineering. C, Materials for biological applications
Nov 24, 2016
Applying scaffolds as a bed to enhance cell proliferation and even differentiation is one of the treatment of retina diseases such as age-related macular degeneration (AMD) which deteriorating photoreceptors and finally happening blindness. In this s...
Effect of actuating cell source on locomotion of organic living machines with electrocompacted collagen skeleton.
Bioinspiration & biomimetics
May 9, 2016
In robotics, there is a need for small scale, compliant actuators for use in medical applications or minimally invasive environmental monitoring. Biohybrid devices offer one solution to this need by using muscle cells to actuate compliant scaffolds. ...
Optimized Repopulation of Tendon Hydrogel: Synergistic Effects of Growth Factor Combinations and Adipose-Derived Stem Cells.
Hand (New York, N.Y.)
Mar 15, 2016
Tendon-derived extracellular matrix (ECM) hydrogel has been shown to augment tendon healing in vivo. We hypothesized that reseeding of the gel with adipose-derived stem cells (ASCs) could further assist repopulation of the gel and that combinations ...
Optimizing parameters on alignment of PCL/PGA nanofibrous scaffold: An artificial neural networks approach.
International journal of biological macromolecules
Oct 27, 2014
This paper proposes an artificial neural networks approach to finding the effects of electrospinning parameters on alignment of poly(ɛ-caprolactone)/poly(glycolic acid) blend nanofibers. Four electrospinning parameters, namely total polymer concentra...
Beyond 3D Printing: How AI is Shaping the Future of Craniomaxillofacial Bone Tissue Engineering.
ACS biomaterials science & engineering
Jun 9, 2025
This perspective focuses on the potential of artificial intelligence (AI) in craniomaxillofacial (CMF) bone tissue engineering, mitigating current challenges, and driving the development of tailored biomaterials and clinical translation. CMF bone tis...
Comparative analysis of deep learning models for predicting biocompatibility in tissue scaffold images.
Computers in biology and medicine
Jun 1, 2025
MOTIVATION: Bioprinting enables the creation of complex tissue scaffolds, which are vital for tissue engineering. However, predicting scaffold biocompatibility before fabrication remains a critical challenge, potentially leading to inefficiencies and...
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