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Tissue Scaffolds

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Controlled surface morphology and hydrophilicity of polycaprolactone toward human retinal pigment epithelium cells.

Materials science & engineering. C, Materials for biological applications
Applying scaffolds as a bed to enhance cell proliferation and even differentiation is one of the treatment of retina diseases such as age-related macular degeneration (AMD) which deteriorating photoreceptors and finally happening blindness. In this s...

Optimized Repopulation of Tendon Hydrogel: Synergistic Effects of Growth Factor Combinations and Adipose-Derived Stem Cells.

Hand (New York, N.Y.)
Tendon-derived extracellular matrix (ECM) hydrogel has been shown to augment tendon healing in vivo. We hypothesized that reseeding of the gel with adipose-derived stem cells (ASCs) could further assist repopulation of the gel and that combinations ...

[A PRELIMINARY STUDY ON SMALL INTESTINAL SUBMUCOSA-SILK COMPOSITE SCAFFOLD TO RECONSTRUCT ANTERIOR CRUCIATE LIGAMENT].

Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery
OBJECTIVE: To prepare the small intestinal submucosa (SIS)-silk composite scaffold for anterior cruciate ligament (ACL) reconstruction, and to evaluate its properties of biomechanics, biocompatibility, and the influence on synovial fluid leaking into...

Three-dimensional heterogeneous assembly of coded microgels using an untethered mobile microgripper.

Lab on a chip
Three-dimensional (3D) heterogeneous assembly of coded microgels in enclosed aquatic environments is demonstrated using a remotely actuated and controlled magnetic microgripper by a customized electromagnetic coil system. The microgripper uses differ...

Optimizing parameters on alignment of PCL/PGA nanofibrous scaffold: An artificial neural networks approach.

International journal of biological macromolecules
This paper proposes an artificial neural networks approach to finding the effects of electrospinning parameters on alignment of poly(ɛ-caprolactone)/poly(glycolic acid) blend nanofibers. Four electrospinning parameters, namely total polymer concentra...

Effect of actuating cell source on locomotion of organic living machines with electrocompacted collagen skeleton.

Bioinspiration & biomimetics
In robotics, there is a need for small scale, compliant actuators for use in medical applications or minimally invasive environmental monitoring. Biohybrid devices offer one solution to this need by using muscle cells to actuate compliant scaffolds. ...

Biodegradable microrobots for targeting cell delivery.

Medical hypotheses
These days, cell delivery is considered a potential method for treatment of many genetic diseases or tissue regeneration applications. In conventional cell delivery methods, cells are encapsulated in or cultured on biocompatible polymers. However, th...

Predicting degradation rate of genipin cross-linked gelatin scaffolds with machine learning.

Materials science & engineering. C, Materials for biological applications
Genipin can improve weak mechanical properties and control high degradation rate of gelatin, as a cross-linker of gelatin which is widely used in tissue engineering. In this study, genipin cross-linked gelatin biodegradable porous scaffolds with diff...

Soft Ring-Shaped Cellu-Robots with Simultaneous Locomotion in Batches.

Advanced materials (Deerfield Beach, Fla.)
Untethered mini-robots can move single cells or aggregates to build complex constructs in confined spaces and may enable various biomedical applications such as regenerative repair in medicine and biosensing in bioengineering. However, a significant ...