AIMC Topic: Unsupervised Machine Learning

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Integrating biological knowledge based on functional annotations for biclustering of gene expression data.

Computer methods and programs in biomedicine
Gene expression data analysis is based on the assumption that co-expressed genes imply co-regulated genes. This assumption is being reformulated because the co-expression of a group of genes may be the result of an independent activation with respect...

Molecular classification of amyotrophic lateral sclerosis by unsupervised clustering of gene expression in motor cortex.

Neurobiology of disease
Amyotrophic lateral sclerosis (ALS) is a rapidly progressive and ultimately fatal neurodegenerative disease, caused by the loss of motor neurons in the brain and spinal cord. Although 10% of ALS cases are familial (FALS), the majority are sporadic (S...

Renal Transplant Survival Prediction From Unsupervised Deep Learning-Based Radiomics on Early Dynamic Contrast-Enhanced MRI.

Academic radiology
RATIONALE AND OBJECTIVES: End-stage renal disease is characterized by an irreversible decline in kidney function. Despite a risk of chronic dysfunction of the transplanted kidney, renal transplantation is considered the most effective solution among ...

Unsupervised Accuracy Estimation for Brain-Computer Interfaces Based on Selective Auditory Attention Decoding.

IEEE transactions on bio-medical engineering
OBJECTIVE: Selective auditory attention decoding (AAD) algorithms process brain data such as electroencephalography to decode to which of multiple competing sound sources a person attends. Example use cases are neuro-steered hearing aids or communica...

Revisiting Abnormalities of Ventricular Depolarization: Redefining Phenotypes and Associated Outcomes Using Tree-Based Dimensionality Reduction.

Journal of the American Heart Association
BACKGROUND: Abnormal ventricular depolarization, evident as a broad QRS complex on an ECG, is traditionally categorized into left bundle-branch block (LBBB) and right bundle-branch block or nonspecific intraventricular conduction delay. This categori...

A Weight-Aware-Based Multisource Unsupervised Domain Adaptation Method for Human Motion Intention Recognition.

IEEE transactions on cybernetics
Accurate recognition of human motion intention (HMI) is beneficial for exoskeleton robots to improve the wearing comfort level and achieve natural human-robot interaction. A classifier trained on labeled source subjects (domains) performs poorly on u...

Supervised and unsupervised learning for lung perfusion data segmentation in electrical impedance tomography.

Biomedical physics & engineering express
: Effective lung gas exchange relies on the balance between alveolar ventilation and perfusion, which can be disrupted in mechanically ventilated patients. Lung perfusion assessment using electrical impedance tomography (EIT) typically involves a sud...

Unsupervised Adaptive Deep Learning Framework for Video Denoising in Light Scattering Imaging.

Analytical chemistry
Light scattering is a powerful tool that has been widely applied in various scenarios, such as nanoparticle analysis, single-cell measurement, and blood flow monitoring. However, noise is always a concerning and challenging issue in light scattering ...

Unsupervised discovery of clinical disease signatures using probabilistic independence.

Journal of biomedical informatics
OBJECTIVE: This study uses probabilistic independence to disentangle patient-specific sources of disease and their signatures in Electronic Health Record (EHR) data.

Unsupervised detection of sub-sequence anomalies in epilepsy EEG.

Computers in biology and medicine
Seizures in electroencephalogram (EEG) data constitute a special case of sub-sequence anomalies in multivariate data with numerous challenges. These challenges include the irregular patterns exhibited even by the same individual, making seizures diff...