AIMC Topic: Ventricular Remodeling

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Epicardial adipose tissue, myocardial remodelling and adverse outcomes in asymptomatic aortic stenosis: a post hoc analysis of a randomised controlled trial.

Heart (British Cardiac Society) Jun 26, 2025
BACKGROUND: Epicardial adipose tissue represents a metabolically active visceral fat depot that is in direct contact with the left ventricular myocardium. While it is associated with coronary artery disease, little is known regarding its role in aort...
Female Aged Male Ventricular Function, Left Echocardiography Humans Prospective Studies Ventricular Remodeling Asymptomatic Diseases Computed Tomography Angiography Pericardium Epicardial Adipose Tissue Middle Aged Disease Progression Severity of Illness Index Aortic Valve Stenosis Adipose Tissue
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Epistasis regulates genetic control of cardiac hypertrophy.

Nature cardiovascular research Jun 5, 2025
Although genetic variant effects often interact nonadditively, strategies to uncover epistasis remain in their infancy. Here we develop low-signal signed iterative random forests to elucidate the complex genetic architecture of cardiac hypertrophy, u...
Epistasis, Genetic Induced Pluripotent Stem Cells Connectin Deep Learning Phenotype Receptor, IGF Type 1 Genome-Wide Association Study Female Heart Failure Gene Regulatory Networks Aged Humans Ventricular Remodeling Genetic Predisposition to Disease Male Myocytes, Cardiac Magnetic Resonance Imaging Middle Aged Hypertrophy, Left Ventricular
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Artificial intelligence-derived left ventricular strain in echocardiography in patients treated with chemotherapy.

The international journal of cardiovascular imaging Jul 23, 2024
Global longitudinal strain (GLS) is an echocardiographic measure to detect chemotherapy-related cardiovascular dysfunction. However, its limited availability and the needed expertise may restrict its generalization. Artificial intelligence (AI)-based...
Female Reproducibility of Results Aged Aged, 80 and over Male Humans Artificial Intelligence Retrospective Studies Antineoplastic Agents Predictive Value of Tests Heart Ventricles Ventricular Remodeling Ventricular Dysfunction, Left Ventricular Function, Left Stroke Volume Echocardiography Middle Aged Neoplasms Image Interpretation, Computer-Assisted Observer Variation Cardiotoxicity
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Soft robotic patient-specific hydrodynamic model of aortic stenosis and ventricular remodeling.

Science robotics Feb 22, 2023
Aortic stenosis (AS) affects about 1.5 million people in the United States and is associated with a 5-year survival rate of 20% if untreated. In these patients, aortic valve replacement is performed to restore adequate hemodynamics and alleviate symp...
Hydrodynamics Transcatheter Aortic Valve Replacement Humans United States Treatment Outcome Aortic Valve Stenosis Robotics Ventricular Remodeling
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Unsupervised clustering of patients with severe aortic stenosis: A myocardial continuum.

Archives of cardiovascular diseases Sep 29, 2022
BACKGROUND: Traditional statistics, based on prediction models with a limited number of prespecified variables, are probably not adequate to provide an appropriate classification of a condition that is as heterogeneous as aortic stenosis (AS).
Cluster Analysis Aortic Valve Stenosis Aortic Valve Ventricular Remodeling Artificial Intelligence Female Aged Male Severity of Illness Index Humans
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Artificial Intelligence and Cardiovascular Magnetic Resonance Imaging in Myocardial Infarction Patients.

Current problems in cardiology Jul 21, 2022
Cardiovascular magnetic resonance (CMR) is an important cardiac imaging tool for assessing the prognostic extent of myocardial injury after myocardial infarction (MI). Within the context of clinical trials, CMR is also useful for assessing the effica...
Magnetic Resonance Imaging Myocardial Infarction Ventricular Remodeling Humans Artificial Intelligence Reproducibility of Results
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Deep learning to diagnose cardiac amyloidosis from cardiovascular magnetic resonance.

Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance Dec 7, 2020
BACKGROUND: Cardiovascular magnetic resonance (CMR) is part of the diagnostic work-up for cardiac amyloidosis (CA). Deep learning (DL) is an application of artificial intelligence that may allow to automatically analyze CMR findings and establish the...
Myocardium Male Humans Amyloid Neuropathies, Familial Ventricular Remodeling Female Ventricular Function, Left Immunoglobulin Light-chain Amyloidosis Cardiomyopathy, Hypertrophic Deep Learning Reproducibility of Results Hypertrophy, Left Ventricular Image Processing, Computer-Assisted Aged Magnetic Resonance Imaging, Cine Predictive Value of Tests Aged, 80 and over
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A Comparison of Three-Dimensional Speckle Tracking Echocardiography Parameters in Predicting Left Ventricular Remodeling.

Journal of healthcare engineering Jul 30, 2020
Three-dimensional speckle tracking echocardiography (3D STE) is an emerging noninvasive method for predicting left ventricular remodeling (LVR) after acute myocardial infarction (AMI). Previous studies analyzed the predictive value of 3D STE with tra...
Imaging, Three-Dimensional Models, Statistical Predictive Value of Tests Area Under Curve Coronary Angiography Percutaneous Coronary Intervention Myocardial Infarction Heart Ventricles Ventricular Remodeling Ventricular Dysfunction, Left Humans Sensitivity and Specificity Machine Learning Male Reproducibility of Results Female Echocardiography Risk Factors Middle Aged Aged ROC Curve Adult
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Clinical Significance of Circulating Cardiomyocyte-Specific Cell-Free DNA in Patients With Heart Failure: A Proof-of-Concept Study.

The Canadian journal of cardiology Oct 19, 2019
We investigated clinical significance of cell-free DNA (cfDNA) in heart failure. This study enrolled 32 heart failure patients and 28 control subjects. Total cfDNA levels were not different between groups (P = 0.343). Bisulfite-digital polymerase cha...
Cell Death Aged Humans Heart Failure Male Natriuretic Peptide, Brain Stroke Volume Biomarkers Ventricular Remodeling Correlation of Data Echocardiography Ventricular Dysfunction, Left Prognosis Liquid Biopsy Cell-Free Nucleic Acids Female Myocytes, Cardiac
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Ventricular geometry-regularized QRSd predicts cardiac resynchronization therapy response: machine learning from crosstalk between electrocardiography and echocardiography.

The international journal of cardiovascular imaging May 18, 2019
Up to one-third of patients selected by current guidelines do not respond to cardiac resynchronization therapy (CRT), the aim of this study was to find out novel analytical approaches to improve pre-implantation CRT response prediction. Among 31 pre-...
Echocardiography Middle Aged Electrocardiography Treatment Outcome Humans Predictive Value of Tests Female Support Vector Machine Ventricular Remodeling Clinical Decision-Making Signal Processing, Computer-Assisted Aged Image Interpretation, Computer-Assisted Patient Selection Aged, 80 and over Heart Failure Male Cardiac Resynchronization Therapy Ventricular Function, Left
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