Neonatal hypoxic-ischemic (H-I) brain injury, a leading cause of neurodevelopmental disabilities, severely affects the metabolically active and neurogenic hippocampus. To investigate its acute effects and identify drug targets for early therapeutic w...
BACKGROUND: Poly-victimization (PV), encompassing multiple forms of victimization including physical abuse, emotional maltreatment, neglect, and peer violence, poses a significant public health challenge among children, particularly in rural areas wi...
Journal of neuroengineering and rehabilitation
Jul 5, 2025
BACKGROUND: Hand dysfunction significantly affects independence after stroke, with outcomes varying across individuals. Exploring biomarkers associated with the paretic hand can improve the prognosis and guide personalized rehabilitation. However, wh...
This study assesses the influence of social support, self-esteem, depression, and education on psychological resilience among men who have sex with men (MSM) to inform policy-making. Data were collected from 1,070 MSM via an online survey in Zhejiang...
OBJECTIVE: To develop and validate an interpretable machine learning (ML)-based frailty risk prediction model that combines real-time health data with validated scale assessments for enhanced decision-making and targeted health management in integrat...
BACKGROUND AND OBJECTIVE: Chronic obstructive pulmonary disease (COPD), a progressively worsening respiratory condition, severely impacts patient quality of life. Early risk assessment can improve treatment outcomes and lessen healthcare burdens. How...
BACKGROUND: Immune imbalance caused by imbalanced helper T(Th)17/regulatory T (Treg) and follicular helper T (Tfh)/follicular regulatory T (Tfr) cells drives the onset of rheumatoid arthritis (RA) fundamentally. Tryptophan (Trp) metabolism is crucial...
The rapid advancement of the Internet of Medical Things (IoMT) has revolutionized remote healthcare monitoring, enabling real-time disease detection and patient care. This research introduces a novel AI-driven telemedicine framework that integrates I...
INTRODUCTION: Diabetic retinopathy (DR) is a leading cause of vision loss. With an estimated 38.4 million Americans diagnosed with DM, the disease exerts a significant burden on healthcare systems, especially in rural areas where access to care is li...
BACKGROUND: The complex pathogenesis of Alzheimer's disease (AD) has resulted in limited current biomarkers for its classification and diagnosis, necessitating further investigation into reliable universal biomarkers or combinations.
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