AI Medical Compendium Journal:
Clinical and experimental medicine

Showing 1 to 10 of 10 articles

Predicting the risk of ibrutinib in combination with R-ICE in patients with relapsed or refractory DLBCL using explainable machine learning algorithms.

Clinical and experimental medicine
Relapsed or refractory diffuse large B-cell lymphoma (DLBCL) poses significant therapeutic challenges due to heterogeneous patient outcomes. This study aimed to evaluate the efficacy of the ibrutinib plus R-ICE regimen and to leverage explainable mac...

Machine learning and single-cell analysis uncover distinctive characteristics of CD300LG within the TNBC immune microenvironment: experimental validation.

Clinical and experimental medicine
Investigating the essential function of CD300LG within the tumor microenvironment in triple-negative breast cancer (TNBC). Transcriptomic and single-cell data from TNBC were systematically collected and integrated. Four machine learning algorithms we...

Machine learning for the prediction of diabetes-related amputation: a systematic review and meta-analysis of diagnostic test accuracy.

Clinical and experimental medicine
Although machine learning is frequently used in medicine for predictive purposes, its accuracy in diabetes-related amputation (DRA) remains unclear. From establishing the database until December 2024, we conducted a comprehensive search of PubMed, We...

Application of artificial intelligence in rheumatic disease: a bibliometric analysis.

Clinical and experimental medicine
The utilization of artificial intelligence (AI) in rheumatic diseases has enhanced the diagnostic accuracy of rheumatic diseases, enabled the prediction of patient outcomes, expanded treatment options, and facilitated the provision of individualized ...

Survival trend and outcome prediction for pediatric Hodgkin and non-Hodgkin lymphomas based on machine learning.

Clinical and experimental medicine
Pediatric Hodgkin and non-Hodgkin lymphomas differ from adult cases in biology and management, yet there is a lack of survival analysis tailored to pediatric lymphoma. We analyzed lymphoma data from 1975 to 2018, comparing survival trends between 7,8...

Identification of antigen-presentation related B cells as a key player in Crohn's disease using single-cell dissecting, hdWGCNA, and deep learning.

Clinical and experimental medicine
Crohn's disease (CD) arises from intricate intercellular interactions within the intestinal lamina propria. Our objective was to use single-cell RNA sequencing to investigate CD pathogenesis and explore its clinical significance. We identified a dist...

A review of research on eligibility criteria for clinical trials.

Clinical and experimental medicine
The purpose of this paper is to systematically sort out and analyze the cutting-edge research on the eligibility criteria of clinical trials. Eligibility criteria are important prerequisites for the success of clinical trials. It directly affects the...

A machine learning-based prediction model for colorectal liver metastasis.

Clinical and experimental medicine
Colorectal liver metastasis (CRLM) is a primary factor contributing to poor prognosis and metastasis in colorectal cancer (CRC) patients. This study aims to develop and validate a machine learning (ML)-based risk prediction model using conventional c...

Binary classification of gynecological cancers based on ATR-FTIR spectroscopy and machine learning using urine samples.

Clinical and experimental medicine
Making an early diagnosis of cancer still in the early stages, when completely asymptomatic, is the challenge modern medicine has been setting for several decades. In gynecology, no effective screening has yet been found and approved for endometrial ...

Development of a prognostic model for osteosarcoma based on macrophage polarization-related genes using machine learning: implications for personalized therapy.

Clinical and experimental medicine
While neoadjuvant chemotherapy combined with surgical resection has improved the prognosis for patients with osteosarcoma, its impact on metastatic and recurrent cases remains limited. Immunotherapy is emerging as a promising alternative. However, th...