AI Medical Compendium Journal:
EBioMedicine

Showing 1 to 10 of 122 articles

Prediction of acute and chronic kidney diseases during the post-covid-19 pandemic with machine learning models: utilizing national electronic health records in the US.

EBioMedicine
BACKGROUND: COVID-19 has been linked to acute kidney injury (AKI) and chronic kidney disease (CKD), but machine learning (ML) models predicting these risks post-pandemic have been absent. We aimed to use large electronic health records (EHR) and ML a...

Artificial intelligence-driven genotype-epigenotype-phenotype approaches to resolve challenges in syndrome diagnostics.

EBioMedicine
BACKGROUND: Decisions to split two or more phenotypic manifestations related to genetic variations within the same gene can be challenging, especially during the early stages of syndrome discovery. Genotype-based diagnostics with artificial intellige...

Deep learning informed multimodal fusion of radiology and pathology to predict outcomes in HPV-associated oropharyngeal squamous cell carcinoma.

EBioMedicine
BACKGROUND: We aim to predict outcomes of human papillomavirus (HPV)-associated oropharyngeal squamous cell carcinoma (OPSCC), a subtype of head and neck cancer characterized with improved clinical outcome and better response to therapy. Pathology an...

AI in radiological imaging of soft-tissue and bone tumours: a systematic review evaluating against CLAIM and FUTURE-AI guidelines.

EBioMedicine
BACKGROUND: Soft-tissue and bone tumours (STBT) are rare, diagnostically challenging lesions with variable clinical behaviours and treatment approaches. This systematic review aims to provide an overview of Artificial Intelligence (AI) methods using ...

Identification of heart failure subtypes using transformer-based deep learning modelling: a population-based study of 379,108 individuals.

EBioMedicine
BACKGROUND: Heart failure (HF) is a complex syndrome with varied presentations and progression patterns. Traditional classification systems based on left ventricular ejection fraction (LVEF) have limitations in capturing the heterogeneity of HF. We a...

Machine learning detection of heteroresistance in Escherichia coli.

EBioMedicine
BACKGROUND: Heteroresistance (HR) is a significant type of antibiotic resistance observed for several bacterial species and antibiotic classes where a susceptible main population contains small subpopulations of resistant cells. Mathematical models, ...

De Novo exposomic geospatial assembly of chronic disease regions with machine learning & network analysis.

EBioMedicine
BACKGROUND: Determining spatial relationships between diseases and the exposome is limited by available methodologies. aPEER (algorithm for Projection of Exposome and Epidemiological Relationships) uses machine learning (ML) and network analysis to f...

Artificial intelligence-enhanced comprehensive assessment of the aortic valve stenosis continuum in echocardiography.

EBioMedicine
BACKGROUND: Transthoracic echocardiography (TTE) is the primary modality for diagnosing aortic stenosis (AS), yet it requires skilled operators and can be resource-intensive. We developed and validated an artificial intelligence (AI)-based system for...

Why implementing machine learning algorithms in the clinic is not a plug-and-play solution: a simulation study of a machine learning algorithm for acute leukaemia subtype diagnosis.

EBioMedicine
BACKGROUND: Artificial intelligence (AI) and machine learning (ML) algorithms have shown great promise in clinical medicine. Despite the increasing number of published algorithms, most remain unvalidated in real-world clinical settings. This study ai...

Where, why, and how is bias learned in medical image analysis models? A study of bias encoding within convolutional networks using synthetic data.

EBioMedicine
BACKGROUND: Understanding the mechanisms of algorithmic bias is highly challenging due to the complexity and uncertainty of how various unknown sources of bias impact deep learning models trained with medical images. This study aims to bridge this kn...