AI Medical Compendium Journal:
Journal of cellular and molecular medicine

Showing 21 to 30 of 49 articles

Diagnostic Power of MicroRNAs in Melanoma: Integrating Machine Learning for Enhanced Accuracy and Pathway Analysis.

Journal of cellular and molecular medicine Jan 1, 2025
This study identifies microRNAs (miRNAs) with significant discriminatory power in distinguishing melanoma from nevus, notably hsa-miR-26a and hsa-miR-211, which have exhibited diagnostic potential with accuracy of 81% and 78% respectively. To enhance...
Gene Expression Profiling Protein Interaction Maps Gene Regulatory Networks Gene Expression Regulation, Neoplastic Machine Learning Melanoma Biomarkers, Tumor Signal Transduction MicroRNAs Humans
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Enhancing Molecular Network-Based Cancer Driver Gene Prediction Using Machine Learning Approaches: Current Challenges and Opportunities.

Journal of cellular and molecular medicine Jan 1, 2025
Cancer is a complex disease driven by mutations in the genes that play critical roles in cellular processes. The identification of cancer driver genes is crucial for understanding tumorigenesis, developing targeted therapies and identifying rational ...
Machine Learning Neoplasms Protein Interaction Maps Gene Regulatory Networks Humans Neural Networks, Computer Computational Biology Mutation Oncogenes
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Artificial Intelligence-Guided Identification of IGFBP7 as a Critical Indicator in Lactic Metabolism Determines Immunotherapy Response in Stomach Adenocarcinoma.

Journal of cellular and molecular medicine Jan 1, 2025
Due to considerable tumour heterogeneity, stomach adenocarcinoma (STAD) has a poor prognosis and varies in response to treatment, making it one of the main causes of cancer-related mortality globally. Recent data point to a significant role for metab...
Lactic Acid Insulin-Like Growth Factor Binding Proteins Humans Biomarkers, Tumor Artificial Intelligence Male Prognosis Gene Expression Regulation, Neoplastic Cell Line, Tumor Stomach Neoplasms Cell Proliferation Immunotherapy Adenocarcinoma Cell Movement
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TPD52 as a Therapeutic Target Identified by Machine Learning Shapes the Immune Microenvironment in Breast Cancer.

Journal of cellular and molecular medicine Jan 1, 2025
Breast cancer (BRCA) is one of the most common malignancies and a leading cause of cancer-related mortality among women globally. Despite advances in diagnosis and treatment, the heterogeneity of BRCA presents significant challenges for effective man...
Machine Learning Prognosis Female Breast Neoplasms Humans Single-Cell Analysis Computational Biology Gene Expression Regulation, Neoplastic Neoplasm Proteins Tumor Microenvironment Biomarkers, Tumor Gene Expression Profiling Cell Line, Tumor
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Deciphering the Role of SLFN12: A Novel Biomarker for Predicting Immunotherapy Outcomes in Glioma Patients Through Artificial Intelligence.

Journal of cellular and molecular medicine Dec 1, 2024
Gliomas are the most prevalent form of primary brain tumours. Recently, targeting the PD-1 pathway with immunotherapies has shown promise as a novel glioma treatment. However, not all patients experience long-lasting benefits, underscoring the necess...
Gene Expression Regulation, Neoplastic Cell Proliferation Treatment Outcome Glioma Programmed Cell Death 1 Receptor Biomarkers, Tumor Brain Neoplasms Cell Line, Tumor Immunotherapy Artificial Intelligence Prognosis Humans Tumor Microenvironment
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MSA-MaxNet: Multi-Scale Attention Enhanced Multi-Axis Vision Transformer Network for Medical Image Segmentation.

Journal of cellular and molecular medicine Dec 1, 2024
Convolutional neural networks (CNNs) are well established in handling local features in visual tasks; yet, they falter in managing complex spatial relationships and long-range dependencies that are crucial for medical image segmentation, particularly...
Humans Neural Networks, Computer Algorithms Image Processing, Computer-Assisted Diagnostic Imaging
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Building a Risk Scoring Model for ARDS in Lung Adenocarcinoma Patients Using Machine Learning Algorithms.

Journal of cellular and molecular medicine Dec 1, 2024
Lung adenocarcinoma (LUAD), the predominant form of non-small-cell lung cancer, is frequently complicated by acute respiratory distress syndrome (ARDS), which increases mortality risks. Investigating the prognostic implications of ARDS-related genes ...
DNA Copy Number Variations Mutation Adenocarcinoma of Lung Risk Factors Gene Expression Profiling Biomarkers, Tumor Lung Neoplasms Male Gene Expression Regulation, Neoplastic Machine Learning Risk Assessment Respiratory Distress Syndrome Algorithms Prognosis Humans Female
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GD-Net: An Integrated Multimodal Information Model Based on Deep Learning for Cancer Outcome Prediction and Informative Feature Selection.

Journal of cellular and molecular medicine Dec 1, 2024
Multimodal information provides valuable resources for cancer prognosis and survival prediction. However, the computational integration of this heterogeneous data information poses significant challenges due to the complex interactions between molecu...
Neoplasms Deep Learning Liver Neoplasms Computational Biology Gene Expression Regulation, Neoplastic DNA Methylation MicroRNAs Humans Algorithms Prognosis Biomarkers, Tumor
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Unveiling Varied Cell Death Patterns in Lung Adenocarcinoma Prognosis and Immunotherapy Based on Single-Cell Analysis and Machine Learning.

Journal of cellular and molecular medicine Nov 1, 2024
Programmed cell death (PCD) pathways hold significant influence in the etiology and progression of a variety of cancer forms, particularly offering promising prognostic markers and clues to drug sensitivity for lung adenocarcinoma (LUAD) patients. We...
Cell Line, Tumor Female Humans Single-Cell Analysis Tumor Microenvironment Gene Expression Regulation, Neoplastic Lung Neoplasms Machine Learning Biomarkers, Tumor Apoptosis Immunotherapy Prognosis Male Cell Death Adenocarcinoma of Lung
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Deep Learning and Single-Cell Sequencing Analyses Unveiling Key Molecular Features in the Progression of Carotid Atherosclerotic Plaque.

Journal of cellular and molecular medicine Nov 1, 2024
Rupture of advanced carotid atherosclerotic plaques increases the risk of ischaemic stroke, which has significant global morbidity and mortality rates. However, the specific characteristics of immune cells with dysregulated function and proven biomar...
Aged Male Middle Aged Disease Progression Humans Biomarkers Female Sequence Analysis, RNA Plaque, Atherosclerotic Carotid Artery Diseases Gene Expression Profiling Deep Learning Single-Cell Analysis Monocytes
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