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Molecular detection of hrHPV-induced high-grade squamous intraepithelial lesions of the cervix through a targeted RNA next generation sequencing assay.
Molecular medicine (Cambridge, Mass.)
May 30, 2025
BACKGROUND: Cervical cancer screening programs are increasingly relying on sensitive molecular approaches as primary tests to detect high-risk human papillomaviruses (hrHPV), the causative agents of cervix cancer. Although hrHPV infection is a pre-re...
Clinical, genetic, and sociodemographic predictors of symptom severity after internet-delivered cognitive behavioural therapy for depression and anxiety.
BMC psychiatry
May 30, 2025
BACKGROUND: Internet-delivered cognitive behavioural therapy (ICBT) is an effective and accessible treatment for mild to moderate depression and anxiety disorders. However, up to 50% of patients do not achieve sufficient symptom relief. Identifying p...
Effect of visceral fat on onset of metabolic syndrome.
Scientific reports
May 30, 2025
This study analysed the effects of visceral fat on metabolic syndrome (MetS) and developed an algorithm to predict its onset using health examination data from the Iwaki Health Promotion Project in Japan. The dataset included 213 cases of MetS onset ...
Upper limb human-exoskeleton system motion state classification based on semg: application of CNN-BiLSTM-attention model.
Scientific reports
May 30, 2025
This study aims to classify five typical motion states of the human upper limb based on surface electromyography signals, thereby supporting the real-time control system of an assistive upper limb exoskeleton. We propose a deep learning model combini...
Integrated plasma and vegetation proteomic characterization of infective endocarditis for early diagnosis and treatment.
Nature communications
May 30, 2025
Infective endocarditis, a life-threatening condition, poses challenges for early diagnosis and personalized treatment due to insufficient biomarkers and limited understanding of its pathophysiology. Here, we performed proteomic profiling of plasma an...
A qualitative analysis of college students' interest in mHealth solutions.
Frontiers in public health
May 30, 2025
This study explores college students' perceptions of an AI-driven mHealth application designed to promote well-being. With rising mental health challenges in academic settings, students increasingly seek digital tools that provide holistic support fo...
Associations of greenhouse gases, air pollutants and dynamics of scrub typhus incidence in China: a nationwide time-series study.
BMC public health
May 29, 2025
BACKGROUND: Environmental factors have been identified as significant risk factors for scrub typhus. However, the impact of inorganic compounds such as greenhouse gases and air pollutants on the incidence of scrub typhus has not been evaluated.
Relapse prediction using wearable data through convolutional autoencoders and clustering for patients with psychotic disorders.
Scientific reports
May 29, 2025
Relapse of psychotic disorders occurs commonly even after appropriate treatment. Digital phenotyping becomes essential to achieve remote monitoring for mental conditions. We applied a personalized approach using neural-network-based anomaly detection...
Menopausal hormone therapy and the female brain: Leveraging neuroimaging and prescription registry data from the UK Biobank cohort.
eLife
May 29, 2025
BACKGROUND: Menopausal hormone therapy (MHT) is generally thought to be neuroprotective, yet results have been inconsistent. Here, we present a comprehensive study of MHT use and brain characteristics in females from the UK Biobank.
Exploring the medical ethical limitations of GPT-4 in clinical decision-making scenarios: a pilot survey.
Frontiers in public health
May 29, 2025
BACKGROUND: This study aims to conduct an examination of GPT-4's tendencies when confronted with ethical dilemmas, as well as to ascertain their ethical limitations within clinical decision-makings.
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