BACKGROUND: Depression causes significant physical and psychosocial morbidity. Predicting persistence of depressive symptoms could permit targeted prevention, and lessen the burden of depression. Machine learning is a rapidly expanding field, and suc...
The journal of applied laboratory medicine
Dec 20, 2018
BACKGROUND: Therapeutic efficacy and toxicity of thiopurine drugs (used as anticancer and immunosuppressant agents) are affected by thiopurine S-methyltransferase (TPMT) enzyme activity. genotype and/or phenotype is used to predict the risk for adve...
BACKGROUND: The standard approaches to diagnosing autism spectrum disorder (ASD) evaluate between 20 and 100 behaviors and take several hours to complete. This has in part contributed to long wait times for a diagnosis and subsequent delays in access...
Age-associated deterioration of cellular physiology leads to pathological conditions. The ability to detect premature aging could provide a window for preventive therapies against age-related diseases. However, the techniques for determining cellular...
BACKGROUND: Emergency admissions are a major source of healthcare spending. We aimed to derive, validate, and compare conventional and machine learning models for prediction of the first emergency admission. Machine learning methods are capable of ca...
BACKGROUND: Bipolar disorder (BD) is a severe psychiatric disorder characterized by periodic episodes of manic and depressive symptomatology. Predominant polarity (PP) appears to be an important specifier of BD. The present study employed machine lea...
BACKGROUND: Electronic medical records provide large-scale real-world clinical data for use in developing clinical decision systems. However, sophisticated methodology and analytical skills are required to handle the large-scale datasets necessary fo...
Medical & biological engineering & computing
Nov 3, 2018
This paper presents a unified approach based on the recurrence quantification analysis (RQA) and approximate entropy (ApEn) for the classification of heart rate variability (HRV). In this paper, the optimum tolerance threshold (r) corresponding to Ap...
Skeletal bone age assessment is a widely used standard procedure in both disease detection and growth prediction for children in endocrinology. Conventional manual assessment methods mainly rely on personal experience in observing X-ray images of lef...
INTRODUCTION: the association between the kidneys and hepatitis B is complex. This study aims to determine the prevalence and factors associated with renal disease in people living with hepatitis B virus (PLHBV) in Cotonou.
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