AIMC Topic: Aged

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Prediction of peripheral blood lymphocyte subpopulations after renal transplantation.

Renal failure
Immune monitoring is essential for maintaining immune homeostasis after renal transplantation (RT). Peripheral blood lymphocyte subpopulations (PBLSs) are widely used biomarkers for immune monitoring, yet there is no established standard reference fo...

Prediction of Poor Visual Outcomes at Idiopathic Intracranial Hypertension Diagnosis Using a Supervised Machine Learning Algorithm.

Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society
BACKGROUND: Idiopathic intracranial hypertension (IIH) is a vision-threatening disorder mainly affecting women of a reproductive age. Prompt diagnosis and intervention are vital to prevent vision loss, but validated tools to predict visual outcomes a...

Detection of S1 spike protein in CD16+ monocytes up to 245 days in SARS-CoV-2-negative post-COVID-19 vaccine syndrome (PCVS) individuals.

Human vaccines & immunotherapeutics
Despite over 13 billion SARS-CoV-2 vaccine doses administered globally, persistent post-vaccination symptoms, termed post-COVID-19 vaccine syndrome (PCVS), resemble post-acute sequelae of COVID-19 (PASC). Symptoms like cardiac, vascular, and neurolog...

Predicting survival outcomes in renal cell carcinoma spinal metastases: a multicenter evaluation of existing prognostic systems.

The spine journal : official journal of the North American Spine Society
BACKGROUND CONTEXT: Survival prediction models for patients with spinal metastases are crucial for guiding clinical decision-making and optimizing treatment strategies. Renal cell carcinoma spinal metastases (RCC-SM) present unique challenges due to ...

Human versus machine: deciding on high-stakes surgery in possible cauda equina syndrome.

The spine journal : official journal of the North American Spine Society
BACKGROUND CONTEXT: Cauda equina syndrome (CES) is a spine surgical urgency requiring prompt intervention to prevent neurological deficits. Accurate identification of CES cases needing urgent surgery is essential to avoid long-term sequelae.

Development of a novel machine learning model to automate vertebral column segmentation utilizing biplanar full-body imaging.

The spine journal : official journal of the North American Spine Society
BACKGROUND CONTEXT: Degenerative scoliosis (DS) is a common spinal disorder among adults, characterized by lateral curvature of the spine. Recent advancements in biplanar full-body imaging, a low-dose and weight-bearing X-ray modality, facilitate saf...

Explainable artificial intelligence for prediction of refractory ulcerative colitis: analysis of a Japanese Nationwide Registry.

Annals of medicine
OBJECTIVE: Ulcerative colitis (UC) is a chronic inflammatory bowel disease for which remission is dependent on corticosteroid (CS) treatment. The diversity of disease pathophysiology necessitates optimal case-specific treatment selection. This study ...

A machine learning model for mortality prediction in patients with severe fever with thrombocytopenia syndrome: a prospective, multicenter cohort study.

Emerging microbes & infections
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease that imposes a considerable medical burden. In this study, we enrolled 1,606 SFTS patients, developed and validated machine learning models for mortality prediction,...

Development and external validation of a machine learning model for cardiac valve calcification early screening in dialysis patients: a multicenter study.

Renal failure
BACKGROUND: Cardiac valve calcification (CVC) is common in dialysis patients and associated with increased cardiovascular risk. However, early screening has been limited by cost concerns. This study aimed to develop and validate a machine learning mo...