AIMC Topic: Aged

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Development and Validation of Quantile Regression Forests for Prediction of Reference Quantiles in Handgrip and Chair-Stand Test.

Journal of cachexia, sarcopenia and muscle
BACKGROUND: Muscle strength is one of the key components in the diagnosis of sarcopenia. The aim of this study was to train a machine learning model to predict reference values and percentiles for handgrip strength and chair-stand test (CST), in a la...

[Risk prediction of demoralization syndrome in patients with oral cancer].

Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology
OBJECTIVES: This study aimed to construct a risk prediction model for the occurrence of the demora-lization syndrome in patients with oral cancer and provide a scientific basis for the prevention of this syndrome in patients with oral cancer and the ...

Development of Machine-Learning-Based Models for Detection of Cognitive Impairment in Patients Receiving Maintenance Hemodialysis.

European journal of neurology
BACKGROUND: Cognitive impairment is common but frequently undiagnosed in the dialysis population. We aimed to develop and validate a quick and accurate screening tool using machine-learning-based approaches in them.

Enhanced Early Detection of Colorectal Cancer via Blood Biomarker Combinations Identified Through Extracellular Vesicle Isolation and Artificial Intelligence Analysis.

Journal of extracellular vesicles
Colorectal cancer (CRC) remains a major cause of cancer-related deaths worldwide, with early detection being crucial for improving survival rates. Despite the potential of extracellular vesicles (EVs) as blood biomarkers for CRC diagnosis, their clin...

Theta-Beta/Gamma Coupling Identifies Bothersome Tinnitus Induced by Thalamocortical Dysrhythmia.

Brain and behavior
BACKGROUND: The phantom sound of tinnitus can be an extremely debilitating condition. The thalamocortical dysrhythmia (TCD) hypothesis is a feature of subjective tinnitus; however, its consistency in characterizing different types of tinnitus remains...

Segmentation of Leukoaraiosis on Noncontrast Head CT Using CT-MRI Paired Data Without Human Annotation.

Brain and behavior
OBJECTIVE: Evaluating leukoaraiosis (LA) on CT is challenging due to its low contrast and similarity to parenchymal gliosis. We developed and validated a deep learning algorithm for LA segmentation using CT-MRIFLAIR paired data from a multicenter Kor...

Development of a Diagnostic Prediction Model for Post-Stroke Cognitive Impairment in Acute Large Vessel Occlusion Stroke Using Multimodal MRI and PET/CT: A Study Protocol.

Brain and behavior
OBJECTIVE: Stroke is a leading cause of morbidity and disability worldwide. Post-stroke cognitive impairment (PSCI) significantly affects long-term prognosis in acute anterior circulation large-vessel occlusion stroke (LVO-AIS). This study aims to de...

Do Transformers and CNNs Learn Different Concepts of Brain Age?

Human brain mapping
"Predicted brain age" refers to a biomarker of structural brain health derived from machine learning analysis of T1-weighted brain magnetic resonance (MR) images. A range of machine learning methods have been used to predict brain age, with convoluti...

Brain Aging in Patients With Cardiovascular Disease From the UK Biobank.

Human brain mapping
The brain undergoes complex but normal structural changes during the aging process in healthy adults, whereas deviations from the normal aging patterns of the brain can be indicative of various conditions as well as an increased risk for the developm...

Network Occlusion Sensitivity Analysis Identifies Regional Contributions to Brain Age Prediction.

Human brain mapping
Deep learning frameworks utilizing convolutional neural networks (CNNs) have frequently been used for brain age prediction and have achieved outstanding performance. Nevertheless, deep learning remains a black box as it is hard to interpret which bra...