AIMC Topic: Aged

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Computing 3-Step Theory of Suicide Factor Scores From Veterans Health Administration Clinical Progress Notes.

Suicide & life-threatening behavior
BACKGROUND: Literature on how to translate information extracted from clinical progress notes into numeric scores for 3-step theory of suicide (3ST) factors is nonexistent. We determined which scoring option would best discriminate between patients w...

Development and Validation of a Novel Model to Discriminate Idiosyncratic Drug-Induced Liver Injury and Autoimmune Hepatitis.

Liver international : official journal of the International Association for the Study of the Liver
BACKGROUND AND AIM: Discriminating between idiosyncratic drug-induced liver injury (DILI) and autoimmune hepatitis (AIH) is critical yet challenging. We aim to develop and validate a machine learning (ML)-based model to aid in this differentiation.

Evaluating the Impact of Changes in Artificial Intelligence-derived Case Scores over Time on Digital Breast Tomosynthesis Screening Outcomes.

Radiology. Artificial intelligence
Purpose To evaluate the change in digital breast tomosynthesis artificial intelligence (DBT-AI) case scores over sequential screenings. Materials and Methods This retrospective review included 21 108 female patients (mean age ± SD, 58.1 years ± 11.5)...

Validation of a Deep Learning-Based Method for Accelerating Susceptibility-Weighted Imaging in Clinical Settings.

NMR in biomedicine
Susceptibility-weighted imaging (SWI) has been widely used in clinical contexts, in which the speed of acquisition is frequently a critical issue. In this study, we aim to test the feasibility of a deep learning (DL)-based reconstruction method for a...

A machine learning approach to automate microinfarct and microhemorrhage screening in hematoxylin and eosin-stained human brain tissues.

Journal of neuropathology and experimental neurology
Microinfarcts and microhemorrhages are characteristic lesions of cerebrovascular disease. Although multiple studies have been published, there is no one universal standard criteria for the neuropathological assessment of cerebrovascular disease. In t...

Deep Learning Model for Predicting Immunotherapy Response in Advanced Non-Small Cell Lung Cancer.

JAMA oncology
IMPORTANCE: Only a small fraction of patients with advanced non-small cell lung cancer (NSCLC) respond to immune checkpoint inhibitor (ICI) treatment. For optimal personalized NSCLC care, it is imperative to identify patients who are most likely to b...

A psychologically interpretable artificial intelligence framework for the screening of loneliness, depression, and anxiety.

Applied psychology. Health and well-being
Negative emotions such as loneliness, depression, and anxiety (LDA) are prevalent and pose significant challenges to emotional well-being. Traditional methods of assessing LDA, reliant on questionnaires, often face limitations because of participants...

Beyond electronic health record data: leveraging natural language processing and machine learning to uncover cognitive insights from patient-nurse verbal communications.

Journal of the American Medical Informatics Association : JAMIA
BACKGROUND: Mild cognitive impairment and early-stage dementia significantly impact healthcare utilization and costs, yet more than half of affected patients remain underdiagnosed. This study leverages audio-recorded patient-nurse verbal communicatio...

Deep learning-based classifier for carcinoma of unknown primary using methylation quantitative trait loci.

Journal of neuropathology and experimental neurology
Cancer of unknown primary (CUP) constitutes between 2% and 5% of human malignancies and is among the most common causes of cancer death in the United States. Brain metastases are often the first clinical presentation of CUP; despite extensive patholo...

Development of Machine Learning Algorithms for Identifying Patients With Limited Health Literacy.

Journal of evaluation in clinical practice
RATIONALE: Limited health literacy (HL) leads to poor health outcomes, psychological stress, and misutilization of medical resources. Although interventions aimed at improving HL may be effective, identifying patients at risk of limited HL in the cli...