AIMC Topic: Aged

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Harnessing an Artificial Intelligence-Based Large Language Model With Personal Health Record Capability for Personalized Information Support in Postsurgery Myocardial Infarction: Descriptive Qualitative Study.

Journal of medical Internet research
BACKGROUND: Myocardial infarction (MI) remains a leading cause of morbidity and mortality worldwide. Although postsurgical cardiac interventions have improved survival rates, effective management during recovery remains challenging. Traditional infor...

Identification and validation of programmed cell death related biomarkers for the treatment and prevention COVID-19.

Annals of medicine
PURPOSE: Programmed cell death (PCD) plays a key role in the progression of coronavirus disease 2019 (COVID-19). However, PCD-relevant biomarkers have not been fully discovered. The aim of this study was to explore the PCD-relevant biomarkers for the...

Integrative Analysis of Lactylation-Associated Features in Abdominal Aortic Aneurysm and Its Immune Microenvironment Utilizing scRNA-seq and Bulk RNA Sequencing.

Circulation journal : official journal of the Japanese Circulation Society
BACKGROUND: Abdominal aortic aneurysm (AAA) is a vascular disease strongly associated with immune dysregulation and metabolic disturbances. Although lactate metabolism and its associated process, lactylation, have been implicated in various diseases,...

An artificial intelligence malnutrition screening tool based on electronic medical records.

Clinical nutrition ESPEN
BACKGROUND & AIMS: Nutrition screening is a fundamental step to ensure appropriate intervention in patients with malnutrition. An automatic tool of nutritional risk screening based on electronic health records will improve efficiency and elevate the ...

Machine Learning-Driven Identification of Hematological and Immunological Biomarkers for Predicting Proliferative Diabetic Retinopathy Progression.

Current eye research
PURPOSE: Proliferative Diabetic Retinopathy (PDR) is a severe complication of diabetes characterized by neovascularization and retinal detachment, leading to significant vision loss. This study investigates the predictive power of hematological and i...

Tumor grade-titude: XGBoost radiomics paves the way for RCC classification.

European journal of radiology
This study aimed to develop and evaluate a non-invasive XGBoost-based machine learning model using radiomic features extracted from pre-treatment CT images to differentiate grade 4 renal cell carcinoma (RCC) from lower-grade tumours. A total of 102 R...

A machine learning tool for prediction of vertebral compression fracture following stereotactic body radiation therapy for spinal metastases.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
BACKGROUND AND PURPOSE: The most common adverse event following spine stereotactic body radiotherapy (SBRT) is vertebral compression fracture (VCF). There is interest in the development of patient-specific tools that can predict those at high risk of...

Clinical Validation of a Noninvasive Multi-Omics Method for Multicancer Early Detection in Retrospective and Prospective Cohorts.

The Journal of molecular diagnostics : JMD
Recent studies highlight the promise of blood-based multicancer early detection (MCED) tests for identifying asymptomatic patients with cancer. However, most focus on a single cancer hallmark, thus limiting effectiveness because of cancer's heterogen...

Deep learning based automated left atrial segmentation and flow quantification of real time phase contrast MRI in patients with atrial fibrillation.

The international journal of cardiovascular imaging
Real time 2D phase contrast (RTPC) MRI is useful for flow quantification in atrial fibrillation (AF) patients, but data analysis requires time-consuming anatomical contouring for many cardiac time frames. Our goal was to develop a convolutional neura...