AIMC Topic: Aged

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Development of machine learning models for gait-based classification of incomplete spinal cord injuries and cauda equina syndrome.

Scientific reports
Incomplete tetraplegia, incomplete paraplegia, and cauda equina syndrome are major neurological disorders that significantly reduce patients' quality of life, primarily due to impaired motor function and gait instability. Although conventional neurol...

Towards prehospital risk stratification using deep learning for ECG interpretation in suspected acute coronary syndrome.

BMJ health & care informatics
OBJECTIVES: Most patients presenting with chest pain in the emergency medical services (EMS) setting are suspected of non-ST-elevation acute coronary syndrome (NSTE-ACS). Distinguishing true NSTE-ACS from non-cardiac chest pain based solely on the EC...

Effects of the lumbar support function of wearable robot (Bot Fit) on sitting position.

Biomedical engineering online
BACKGROUND: Sedentary lifestyles can lead to musculoskeletal disorders, but proper sitting posture, particularly maintaining a slight anterior pelvic tilt, helps prevent issues like lower back pain and spinal misalignment. Samsung Electronics wearabl...

Case-control study combined with machine learning techniques to identify key genetic variations in GSK3B that affect susceptibility to diabetic kidney diseases.

BMC endocrine disorders
The role of genetic susceptibility in early warning and precise treatment of diabetic kidney disease (DKD) requires further investigation. A case-control study was conducted to evaluate the predictive effect of GSK3B genetic polymorphisms on the susc...

Multitask deep learning model based on multimodal data for predicting prognosis of rectal cancer: a multicenter retrospective study.

BMC medical informatics and decision making
BACKGROUND: Prognostic prediction is crucial to guide individual treatment for patients with rectal cancer. We aimed to develop and validated a multitask deep learning model for predicting prognosis in rectal cancer patients.

A systematic comparison of short-term and long-term mortality prediction in acute myocardial infarction using machine learning models.

BMC medical informatics and decision making
BACKGROUND AND OBJECTIVE: The machine learning (ML) models for acute myocardial infarction (AMI) are considered to have better predictive ability for mortality compared to conventional risk scoring models. However, previous ML prediction models have ...

A radiogenomics study on F-FDG PET/CT in endometrial cancer by a novel deep learning segmentation algorithm.

BMC cancer
OBJECTIVE: To create an automated PET/CT segmentation method and radiomics model to forecast Mismatch repair (MMR) and TP53 gene expression in endometrial cancer patients, and to examine the effect of gene expression variability on image texture feat...

Research on ischemic stroke risk assessment based on CTA radiomics and machine learning.

BMC medical imaging
BACKGROUND: The study explores the value of a model constructed by integrating CTA-based carotid plaque radiomic features, clinical risk factors, and plaque imaging characteristics for prognosticating the risk of ischemic stroke.

Predicting carbapenem-resistant Pseudomonas aeruginosa infection risk using XGBoost model and explainability.

Scientific reports
The prevalence and spread of carbapenem-resistant Pseudomonas aeruginosa (CRPA) is a global public health problem. This study aims to identify the risk factors of CRPA infection and construct a machine learning model to provide a prediction tool for ...

Epistasis regulates genetic control of cardiac hypertrophy.

Nature cardiovascular research
Although genetic variant effects often interact nonadditively, strategies to uncover epistasis remain in their infancy. Here we develop low-signal signed iterative random forests to elucidate the complex genetic architecture of cardiac hypertrophy, u...