AIMC Topic: Aged
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A longitudinal cohort study uncovers plasma protein biomarkers predating clinical onset and treatment response of rheumatoid arthritis.
Nature communications
Jul 21, 2025
Rheumatoid arthritis (RA) is a systemic inflammatory condition posing challenges in identifying biomarkers for onset, severity and treatment responses. Here we investigate the plasma proteome in a longitudinal cohort of 278 RA patients, alongside 60 ...
Deep learning using nasal endoscopy and T2-weighted MRI for prediction of sinonasal inverted papilloma-associated squamous cell carcinoma: an exploratory study.
European radiology experimental
Jul 21, 2025
BACKGROUND: Detecting malignant transformation of sinonasal inverted papilloma (SIP) into squamous cell carcinoma (SIP-SCC) before surgery is a clinical need. We aimed to explore the value of deep learning (DL) that leverages nasal endoscopy and T2-w...
Open-source convolutional neural network to classify distal radial fractures according to the AO/OTA classification on plain radiographs.
European journal of trauma and emergency surgery : official publication of the European Trauma Society
Jul 21, 2025
PURPOSE: Convolutional Neural Networks (CNNs) have shown promise in fracture detection, but their ability to improve surgeons' inconsistent fracture classification remains unstudied. Therefore, our aim was create and (externally) validate the perform...
Development and validation of a nomogram model to predict postoperative delirium after resection of esophageal cancer.
Scientific reports
Jul 21, 2025
The study aimed to establish and validate a nomogram model to predict postoperative delirium (POD) among esophageal cancer resection patients. Clinical data of 396 patients with esophageal cancer who underwent esophagectomy from November 2020 to June...
Accuracy and acceptability of self-sampling HPV testing in cervical cancer screening: a population-based study in rural Yunnan, China.
Scientific reports
Jul 21, 2025
To evaluate the accuracy and acceptability of self-sampling samples for HPV testing for cervical cancer screening in rural Yunnan of China. In 2022, 3000 women aged 17-69 were recruited and provided self-sampling vaginal samples alongside provider-sa...
Establishment of two pathomic-based machine learning models to predict CLCA1 expression in colon adenocarcinoma.
PloS one
Jul 21, 2025
Chloride channel accessory 1 (CLCA1) is considered a potential prognostic biomarker for colon adenocarcinoma (COAD). The objective of this research was to develop two pathomics models to predict CLCA1 expression from hematoxylin-eosin (H&E) stained p...
Analysis of aPTT predictors after unfractionated heparin administration in intensive care units using machine learning models.
PloS one
Jul 21, 2025
OBJECTIVES: Predicting optimal coagulation control using heparin in intensive care units (ICUs) remains a significant challenge. This study aimed to develop a machine learning (ML) model to predict activated partial thromboplastin time (aPTT) in ICU ...
Development and temporal validation of a nomogram for predicting ICU 28-day mortality in middle-aged and elderly sepsis patients: An eICU database study.
PloS one
Jul 21, 2025
BACKGROUND AND OBJECTIVE: Despite advances in intensive care, sepsis remains a leading cause of mortality in intensive care unit (ICU) patients, especially middle-aged and elderly individuals. Given the limitations of conventional scoring systems and...
Accurate deep-learning model to differentiate dementia severity and diagnosis using a portable electroencephalography device.
Scientific reports
Jul 20, 2025
Mild cognitive impairment (MCI) and dementia pose significant health challenges in aging societies, emphasizing the need for accessible, cost-effective, and noninvasive diagnostic tools. Electroencephalography (EEG) is a promising biomarker, but trad...
Artificial intelligence in coronary angiography: benchmarking the diagnostic accuracy of ChatGPT-4o against interventional cardiologists.
Open heart
Jul 20, 2025
BACKGROUND: The integration of artificial intelligence (AI) into medical diagnostics has significantly impacted cardiology by enhancing diagnostic precision and therapeutic strategies. Coronary artery disease continues to be a leading cause of global...
Coronary Angiography
Radiographic Image Interpretation, Computer-Assisted
Coronary Artery Disease
Humans
Benchmarking
Female
Male
Artificial Intelligence
Coronary Vessels
Reproducibility of Results
Middle Aged
Retrospective Studies
Cardiologists
Aged
Generative Artificial Intelligence
Predictive Value of Tests
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