AIMC Topic: Aged

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AI-driven scientometric analysis with recency insights: lower urinary tract symptoms in older and frail populations.

World journal of urology
PURPOSE: This artificial intelligence (AI)-driven scientometric analysis, conducted using the Mynd discovery platform, explores research trends in lower urinary tract symptoms (LUTS) among older patients. By applying its novel recency metric, the stu...

Development of a risk prediction model for sepsis-related delirium based on multiple machine learning approaches and an online calculator.

PloS one
BACKGROUND: Sepsis-associated delirium (SAD) occurs due to disruptions in neurotransmission linked to inflammatory responses from infections. It poses significant challenges in clinical management and is associated with poor outcomes. Survivors often...

Construction of a machine learning-based screening model for IgD myeloma.

Clinica chimica acta; international journal of clinical chemistry
OBJECTIVE: Immunoglobulin D (IgD) myeloma is a rare subtype of multiple myeloma (MM), comprising approximately 1 %-2 % of all MM cases. Owing to the diminished levels of IgD in serum, IgD MM manifests as subtle M protein spikes in routine serum elect...

Future of Alzheimer's detection: Advancing diagnostic accuracy through the integration of qEEG and artificial intelligence.

NeuroImage
This comprehensive review examines the integration of Quantitative Electroencephalography (qEEG) and Artificial Intelligence (AI) in the detection and diagnosis of Alzheimer's Disease (AD). Through systematic analysis of 11 key studies across multipl...

Plasma Metabolomics and Machine Learning Reveals Metabolic Alterations and Diagnostic Biomarkers for Deep Venous Thrombosis in Hypertensive Patients after Traumatic Fracture.

Journal of proteome research
We aimed to explore the metabolic dysregulations and diagnostic biomarkers for post-traumatic deep venous thrombosis (pt-DVT) in hypertensive (HPT) patients after fracture. An untargeted ultraperformance liquid chromatography-mass spectrometry-based ...

Assessing inflammatory protein biomarkers in COPD subjects with and without alpha-1 antitrypsin deficiency.

Respiratory research
RATIONALE: Individuals homozygous for the Alpha-1 Antitrypsin (AAT) Z allele (Pi*ZZ) exhibit heterogeneity in COPD risk. COPD occurrence in non-smokers with AAT deficiency (AATD) suggests that inflammatory processes may contribute to COPD risk indepe...

Multi-transcriptomics predicts clinical outcome in systemically untreated breast cancer patients with extensive follow-up.

Breast cancer research : BCR
BACKGROUND: Prognostic tools for determining patients with indolent breast cancers (BCs) are far from optimal, leading to extensive overtreatment. Several studies have demonstrated mRNAs, lncRNAs and miRNAs to have prognostic potential in BC. Because...

An interpretable machine learning model for predicting bone marrow invasion in patients with lymphoma via F-FDG PET/CT: a multicenter study.

BMC medical informatics and decision making
PURPOSE: Accurate identification of bone marrow invasion (BMI) is critical for determining the prognosis of and treatment strategies for lymphoma. Although bone marrow biopsy (BMB) is the current gold standard, its invasive nature and sampling errors...

Development and external validation of a machine learning model for predicting drug-induced immune thrombocytopenia in a real-world hospital cohort.

BMC medical informatics and decision making
BACKGROUND: Drug-induced immune thrombocytopenia (DITP) is a rare but potentially life-threatening adverse drug reaction, often underrecognized due to its nonspecific presentation and the lack of real-time diagnostic tools. Early identification of at...

Interpretable prediction of hospital mortality in bleeding critically ill patients based on machine learning and SHAP.

BMC medical informatics and decision making
BACKGROUND: Hemorrhage is a prevalent and critical condition in the intensive care unit (ICU), characterized by high incidence, elevated mortality rates, and substantial therapeutic challenges. Accurate prediction of mortality in patients with hemorr...