AIMC Topic: Aged

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Axillary lymph node dissection offers no survival benefit in breast cancer patients with sentinel lymph node micrometastases after neoadjuvant therapy.

Clinical and experimental medicine
The role of axillary lymph node dissection (ALND) in breast cancer patients with sentinel lymph node (SLN) micrometastases, particularly after neoadjuvant therapy, remains debated. The present study aimed to assess whether adding ALND provides a surv...

The CT-based deep learning model outperforms traditional anatomical classification models in preoperatively predicting complications and risk grade in partial nephrectomy.

World journal of urology
PURPOSE: A deep learning model integrating CT radiomics and clinical features was developed to predict perioperative complications and risk grade in patients undergoing partial nephrectomy, and was compared to traditional anatomical classification mo...

Identification of key diagnostic and prognostic biomarkers for aortic valve stenosis with coronary artery disease through immunological profiling integrating proteomics, single-cell sequencing, and machine learning.

Biochemical and biophysical research communications
BACKGROUND: Aortic valve stenosis with coronary artery disease (AS-CAD) represents a common yet complex cardiovascular comorbidity, characterized by multifactorial pathogenesis and a lack of specific serum biomarkers. These limitations hinder early d...

High-acceleration pancreatobiliary MRI with deep learning-based super-resolution reconstruction for evaluating presumed pancreatic intraductal papillary mucinous neoplasm.

Cancer imaging : the official publication of the International Cancer Imaging Society
BACKGROUND: To evaluate the feasibility and diagnostic utility of a deep learning (DL)-based super-resolution (SR) reconstruction algorithm applied to pancreatobiliary MRI for assessing pancreatic intraductal papillary mucinous neoplasms (IPMNs).

Use of machine learning for risk stratification of chest pain patients in the emergency department.

BMC medical informatics and decision making
OBJECTIVE: To improve the initial risk assessment capability for emergency chest pain patients without relying on laboratory test results.

Identification of clinically meaningful, overlapping obstructive respiratory disease subtypes via data-driven approaches in a primary care population.

BMC pulmonary medicine
BACKGROUND: Obstructive respiratory conditions, including asthma, bronchiectasis, and chronic obstructive pulmonary disease (COPD), are increasingly recognised as heterogeneous syndromes with significant overlap. Multiple disease pathways contribute ...

Characterizing immune profiles in hepatocellular carcinoma patients benefiting from pembrolizumab and lenvatinib using machine learning.

BMC cancer
BACKGROUND: Combination immunotherapies, such as pembrolizumab plus lenvatinib (PL), are commonly used in treatment for unresectable hepatocellular carcinoma (uHCC). However, it remains challenging to predict which patients will benefit from this the...

Dual-task walking for early detection of Alzheimer's disease: comparative analysis of tasks using whole-body gait variables.

BMC geriatrics
BACKGROUND: The worldwide rise in dementia creates an urgent need for screening methods that are both sensitive and easy to administer. Dual-task walking-requiring people to walk while performing a second cognitive or motor task-meets these criteria ...

Prediction of advanced chronic kidney disease through retinal fundus images by deep learning.

Scientific reports
This study was developed and evaluated deep learning model for detecting chronic kidney disease (CKD) by retinal fundus images. This study included 42,963 clinical visits from 17,442 patients who underwent retinal fundus examination between October 1...

Artificial intelligence for predicting depression anxiety and stress using psychometric data.

Scientific reports
Mental health is a crucial aspect of overall well-being, yet it is often overlooked due to stigma and limited accessibility to care. This study investigates the ability of artificial intelligence (AI) to predict common psychological conditions, depre...