INTRODUCTION: Neuropsychiatric disorders encompass psychiatric and neurodegenerative diseases. These conditions are particularly challenging to diagnose in the elderly due to their overlapping cognitive, affective, and behavioural symptoms. Recent st...
BACKGROUND: Liver fibrosis is a pathological outcome of chronic liver injury and a hallmark of multiple chronic liver diseases. Magnetic resonance elastography (MRE) provides a non-invasive modality for evaluating the severity of liver fibrosis.
BACKGROUND: Coronary heart disease (CHD) continues to be a leading cause of global morbidity and mortality, with patients undergoing percutaneous coronary intervention (PCI) facing a significant risk of recurrent cardiovascular events. While secondar...
Epidemiology and psychiatric sciences
Oct 20, 2025
AIMS: The epidemiology and age-specific patterns of lifetime suicide attempts (LSA) in China remain unclear. We aimed to examine age-specific prevalence and predictors of LSA among Chinese adults using machine learning (ML).
Vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have demonstrated strong efficacy in preventing symptomatic disease, but adverse cardiovascular side effects have been reported. This study investigated whether noninvasive...
BACKGROUND: Rheumatoid arthritis (RA), particularly seronegative disease, is difficult to diagnose early, which can delay treatment initiation. This study aims to develop a binary DNA methylation (DNAm)-based algorithm to diagnose RA.
BACKGROUND: It remains unclear whether certain individuals with type 2 diabetes (T2D) derive greater cardiovascular benefit from GLP-1 receptor agonists (GLP-1RAs). Here, we integrate individual-level data from cardiovascular outcome trials (CVOTs) a...
BACKGROUND: Rising osteoporosis prevalence among elderly populations and limitations of current single-factor screening methods necessitate development of comprehensive multi-dimensional risk prediction models.
BACKGROUND: Insomnia is a significant independent risk factor for depression and suicidality. However, these conditions often go undetected, particularly in individuals presenting with sleep complaints. This study aimed to develop and validate machin...
BACKGROUND: The clinical significance and contribution of the lipid profile in atherosclerosis are well established. However, further investigation is needed in stroke patients, particularly regarding apolipoprotein B100 (ApoB100), a novel non-tradit...
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