AIMC Topic: Aged

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Deep learning informed multimodal fusion of radiology and pathology to predict outcomes in HPV-associated oropharyngeal squamous cell carcinoma.

EBioMedicine
BACKGROUND: We aim to predict outcomes of human papillomavirus (HPV)-associated oropharyngeal squamous cell carcinoma (OPSCC), a subtype of head and neck cancer characterized with improved clinical outcome and better response to therapy. Pathology an...

Machine learning-based model for predicting all-cause mortality in severe pneumonia.

BMJ open respiratory research
BACKGROUND: Severe pneumonia has a poor prognosis and high mortality. Current severity scores such as Acute Physiology and Chronic Health Evaluation (APACHE-II) and Sequential Organ Failure Assessment (SOFA), have limited ability to help clinicians i...

Bioinformatics and machine learning approaches to explore key biomarkers in muscle aging linked to adipogenesis.

BMC musculoskeletal disorders
Adipogenesis is intricately linked to the onset and progression of muscle aging; however, the relevant biomarkers remain unclear. This study sought to identify key genes associated with adipogenesis in the context of muscle aging. Firstly, gene expre...

Network-based predictive models for artificial intelligence: an interpretable application of machine learning techniques in the assessment of depression in stroke patients.

BMC geriatrics
BACKGROUND: Depression is a common complication after a stroke that may lead to increased disability and decreased quality of life. The objective of this study was to develop and validate an interpretable predictive model to assess the risk of depres...

Optimizing heart disease diagnosis with advanced machine learning models: a comparison of predictive performance.

BMC cardiovascular disorders
Cardiovascular disease is the leading cause of mortality globally, necessitating precise and prompt predictive instruments to enhance patient outcomes. In recent years, machine learning methodologies have demonstrated significant potential in enhanci...

A stacking ensemble machine learning model for predicting postoperative axial pain intensity in patients with degenerative cervical myelopathy.

Scientific reports
Machine learning (ML) has been extensively utilized to predict complications associated with various diseases. This study aimed to develop ML-based classifiers employing a stacking ensemble strategy to forecast the intensity of postoperative axial pa...

Machine learning analysis of cardiovascular risk factors and their associations with hearing loss.

Scientific reports
Hearing loss poses immense burden worldwide and early detection is crucial. The accurate models identify high-risk groups, enabling timely intervention to improve quality of life. The subtle changes in hearing often go unnoticed, presenting a challen...

Vowel segmentation impact on machine learning classification for chronic obstructive pulmonary disease.

Scientific reports
Vowel-based voice analysis is gaining attention as a potential non-invasive tool for COPD classification, offering insights into phonatory function. The growing need for voice data has necessitated the adoption of various techniques, including segmen...

Deep learning on T2WI to predict the muscle-invasive bladder cancer: a multi-center clinical study.

Scientific reports
To develop a deep learning (DL) model based on MRI to predict muscle-invasive bladder cancer (MIBC). A total of 559 patients, including 521 patients in our center and 38 patients in external centers were collected from 2012 to 2023 to construct the D...