AIMC Topic: Animals

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Protein interactions, network pharmacology, and machine learning work together to predict genes linked to mitochondrial dysfunction in hypertrophic cardiomyopathy.

Scientific reports
This study looked at possible targets for hypertrophic cardiomyopathy (HCM), a condition marked by thickening of the ventricular wall, primarily in the left ventricle. We employed differential gene analysis and weighted gene co-expression network ana...

Transformer-based deep learning enables improved B-cell epitope prediction in parasitic pathogens: A proof-of-concept study on Fasciola hepatica.

PLoS neglected tropical diseases
BACKGROUND: The identification of B-cell epitopes (BCEs) is fundamental to advancing epitope-based vaccine design, therapeutic antibody development, and diagnostics, such as in neglected tropical diseases caused by parasitic pathogens. However, the s...

Using artificial intelligence-based software for an unbiased discrimination of immune cell subtypes in the fracture hematoma and bone marrow of non-osteoporotic and osteoporotic mice.

PloS one
It is well established that the early inflammatory response following fracture is essential for initiating subsequent bone regeneration. An imbalance in inflammation, whether within the innate or adaptive immune response, can result in impaired fract...

A Machine Learning Pipeline for Automated Bolus Segmentation and Area Measurement in Swallowing Videofluoroscopy Images of an Infant Pig Model.

Dysphagia
Feeding efficiency and safety are often driven by bolus volume, which is one of the most common clinical measures of assessing swallow performance. However, manual measurement of bolus area is time-consuming and suffers from high levels of inter-rate...

A method for evaluating the degree of Adipogenic differentiation of porcine cells cultured in suspension based on deep learning.

Food research international (Ottawa, Ont.)
Fat plays a very important role in the quality of meat and meat products. Cell culture based adipocyte differentiation is a crucial step in the production of cell-cultured meat, traditionally relying on quantitative assessments through fluorescence s...

Comparative examination of the chemistry and biology of AI-driven gold NPs in Theranostics: New insights into biosensing, bioimaging, genomics, diagnostics, and therapy.

Nanomedicine : nanotechnology, biology, and medicine
Integrating artificial intelligence (AI) with nanomedicine is transforming Theranostics, driving advances in biosensing, bioimaging, genomics, diagnostics, and treatment. This review highlights the latest advancements in AI-driven nanomedicine, focus...

Interictal network dysfunction and cognitive impairment in epilepsy.

Nature reviews. Neuroscience
Epilepsy is diagnosed when neural networks become capable of generating excessive or hypersynchronous activity patterns that result in observable seizures. In many cases, epilepsy is associated with cognitive comorbidities that persist between seizur...

Honeybee colony soundscapes: Decoding distance-based cues and environmental stressors.

Ecotoxicology and environmental safety
Honey bees play a crucial role in agricultural productivity and ecological stability, yet their interactions with environmental stressors, particularly volatile organic compounds (VOCs) and pollutants, pose significant challenges to their cognitive f...

Unlocking the soundscape of coral reefs with artificial intelligence: pretrained networks and unsupervised learning win out.

PLoS computational biology
Passive acoustic monitoring can offer insights into the state of coral reef ecosystems at low-costs and over extended temporal periods. Comparison of whole soundscape properties can rapidly deliver broad insights from acoustic data, in contrast to de...

Pathogenicity and virulence of lumpy skin disease virus: A comprehensive update.

Virulence
Lumpy skin disease (LSD), which was confined to the Africa for many decades, has expanded its geographical distribution to numerous countries across Asia and Europe in recent years. The LSD virus (LSDV) is a relatively poorly studied virus. Its 151 K...