AIMC Topic: Animals

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Spinal interneuron population dynamics underlying flexible pattern generation.

Nature communications
The mammalian spinal locomotor network is composed of diverse populations of interneurons that collectively orchestrate and execute a range of locomotor behaviors. As the number of identified classes of spinal interneurons constituting the locomotor ...

A gastric retentive robotic capsule enables emergency-prepared and responsive oral drug delivery in canine models.

Science advances
Existing oral drug delivery modalities often fall short in medical emergencies due to the absence of readily deployable, internalized drug storage and delivery mechanisms that combine long-term standby with rapid activation. To address this challenge...

The group-housed pigs attacking and daily behaviors detection and tracking based on improved YOLOv5s and DeepSORT.

PloS one
Automatic detection and tracking of pig behaviors through video surveillance remain challenges due to farm demanding conditions, e.g., illumination conditions and occlusion of one pig from another. The main goal of this study is to develop a deep lea...

Multidimensional strategy for discovering saltiness-enhancing peptides in shrimp heads integrating ultra-high pressure hydrolysis and machine learning.

Food chemistry
This study aims to develop a comprehensive strategy to investigate whether the integration of ultra-high pressure (UHP)-assisted enzymatic hydrolysis with machine learning and molecular docking can effectively identify salty peptides (SPs) from Litop...

Colorimetric sensor array enabled by deep eutectic solvent-regulated anthocyanins and electrospun polylactic acid nanofiber for pork freshness monitoring.

Food chemistry
In this study, we constructed a bilayer colorimetric sensor array with carboxymethyl cellulose, deep eutectic solvent-regulated anthocyanins, and electrospun polylactic acid nanofibers for real-time monitoring pork freshness. The nanofibers were laye...

From Liquid SNEDDS to Solid SNEDDS: A Comprehensive Review of Their Development and Pharmaceutical Applications.

The AAPS journal
The liquid and solid formulations of self-nano-emulsifying drug delivery systems (SNEDDS) have garnered significant attention in the pharmaceutical field for their ability to enhance the solubility and absorption of hydrophobic drugs. While both liqu...

Integrating climate scenarios and advanced modeling to predict freshwater fish invasions: insights from Carassius species in Iran.

Scientific reports
Freshwater ecosystems are increasingly imperiled by the dual pressures of biological invasions and climate change, necessitating robust predictive frameworks for effective management. This study integrates advanced ensemble machine learning (EML) wit...

Coral-Derived Antimicrobial Peptides Identified In Silico from Acropora digitifera Transcriptomes: Potential Candidates Against Resistant Pathogens.

Marine biotechnology (New York, N.Y.)
Antimicrobial resistance is a serious threat to global public health and requires new therapeutic approaches. Antimicrobial peptides (AMP) are recognized as promising candidates to address antimicrobial resistance. AMP can disrupt cell membranes by i...

Neural network tissue and myocytes co-culture system reveals effects of different myocytes on postnatal development of spinal cord neural network.

Cellular and molecular life sciences : CMLS
The interaction between spinal cord neural networks and myocytes in postnatal mammals plays a crucial role in development, and the neural regulation of motor and visceral functions. Here, spinal cord neural network tissue (SC-NNT) was constructed wit...

OpenSpliceAI provides an efficient modular implementation of SpliceAI enabling easy retraining across nonhuman species.

eLife
The SpliceAI deep learning system is currently one of the most accurate methods for identifying splicing signals directly from DNA sequences. However, its utility is limited by its reliance on older software frameworks and human-centric training data...