AIMC Topic: Animals

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Machine learning-based assessment of sustainable extraction methodologies tackling the biotechnological exploitation of Arnica montana extracts.

Food chemistry
Heat-assisted (HAE), ultrasound-assisted (UAE), microwave-assisted (MAE), and pressurized liquid extraction (PLE) represent diverse techniques with distinct physical principles that influence the efficiency and selectivity of bioactive compound recov...

Temporal and spatial patterns of secondary motor cortex calcium activity in cocaine self-administration: A study using miniScope imaging and machine learning.

Neuropharmacology
Addiction is a chronic mental disorder caused by disruptions in brain function. While most research has focused on the medial prefrontal cortex, our recent findings highlight the secondary motor cortex (M2) as a key region modulating cocaine-seeking ...

Polymer microparticles in an evolving drug delivery landscape: challenges and the role of machine learning.

International journal of pharmaceutics
Polymer microparticles (MPs) have long been a cornerstone of long-acting injectable (LAI) drug delivery, offering controlled drug release, reduced dosing frequency, and improved patient adherence. Among these, poly(lactide-co-glycolide) (PLGA)-based ...

Recent advances in nanopharmaceutical strategies for cancer treatment.

Biochemical and biophysical research communications
Next-generation cancer nanomedicines are revolutionizing therapeutic precision through multifunctional, adaptive, and tumor-specific strategies. This review discusses emerging innovations in cancer nanomedicine, including stimuli-responsive nanomedic...

From precision synthesis to cross-industry applications: The future of emerging peptide technologies.

Pharmacological research
Peptides, derived primarily from natural bioactive sources, play essential roles in human physiological processes such as hormone regulation and nerve signal transmission. Recent advances in phage display technology have revolutionized peptide screen...

Microrobots for Antibiotic-Resistant Skin Colony Eradication.

ACS applied materials & interfaces
Self-propelled nano- and micromachines have immense potential as autonomous seek-and-act devices in biomedical applications. In this study, we present microrobots constructed with inherently biocompatible materials and propulsion systems tailored to ...

Photocatalytic microrobots for treating bacterial infections deep within sinuses.

Science robotics
Microrobotic techniques are promising for treating biofilm infections located deep within the human body. However, the presence of highly viscous pus presents a formidable biological barrier, severely restricting targeted and minimally invasive treat...

Accurate Tracking of Locomotory Kinematics in Mice Moving Freely in Three-Dimensional Environments.

eNeuro
Marker-based motion capture (MBMC) is a powerful tool for precise, high-speed, three-dimensional tracking of animal movements, enabling detailed study of behaviors ranging from subtle limb trajectories to broad spatial exploration. Despite its proven...

CATransU-Net: Cross-attention TransU-Net for field rice pest detection.

PloS one
Accurate detection of rice pests in field is a key problem in field pest control. U-Net can effectively extract local image features, and Transformer is good at dealing with long-distance dependencies. A Cross-Attention TransU-Net (CATransU-Net) mode...

Protective effects of minocycline on dermal fibroblast cells from oxidant and apoptotic effects of HO: A comprehensive analysis with Raman spectroscopy and data-driven approach.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Minocycline (Mino) is an antibiotic with neuroprotective, anti-inflammatory, and antioxidant properties. This study investigated the protective effects of Mino against hydrogen peroxide (HO)-induced oxidative damage in dermal fibroblast cells and ana...