BACKGROUND AND OBJECTIVES: Epilepsy is a common neurologic disorder. Although antiseizure medications (ASMs) are the first-line treatment, identifying the most effective ASM for each individual remains a trial-and-error process. Genetic variation may...
Epilepsy is one of the most prevalent neurological disorders, affecting approximately 23 million people in Asia alone. It is a disorder with severe social impacts and is going to progressively damage the brain. It encompasses a wide range of syndrome...
This study assessed ChatGPT's adherence to established management guidelines for status epilepticus (SE) from major neurological societies (NCS, AES, EFNS) and examined how prompt specificity affected the quality of its recommendations. Four prompts ...
International journal of medical informatics
Apr 21, 2025
OBJECTIVE: Dravet Syndrome (DS) is a developmental and epileptic encephalopathy that is characterized by severe, prolonged motor seizures and high resistance to multiple antiseizure medications (ASMs) with multiple comorbidities. Evaluating the effic...
Neonatal seizures are a common medical emergency, necessitating prompt treatment. The most common etiologies include hypoxic-ischemic encephalopathy, ischemic stroke, and intracranial hemorrhage, with numerous other uncommon etiologies. Accurate diag...
INTRODUCTION: To investigate the potential of using artificial intelligence (AI), specifically large language models (LLMs), for synthesizing information in a simulated randomized clinical trial (RCT) for an anti-seizure medication, cenobamate, demon...
Long-term pharmacological treatment is the cornerstone of the management of bipolar disorder (BD). Clinicians typically select mood-stabilizing medications from among several options through trial and error. This process could be optimized by using r...
Carbamazepine (CBZ) and its transformation products (TPs) often occur in aquatic environments in the form of mixtures, posing potential risks to ecosystems. However, establishing standardized protocols for synthesizing, isolating, and acquiring these...
Identifying new anti-seizure medications (ASMs) is difficult due to limitations in animal-based assays. Zebrafish (Danio rerio) serve as a model for chemical and genetic seizures, but current methods for detecting anti-seizure responses are limited b...
Approximately 30%-40% of epilepsy patients do not respond well to adequate anti-seizure medications (ASMs), a condition known as pharmacoresistant epilepsy. The management of pharmacoresistant epilepsy remains an intractable issue in the clinic. Its ...
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