AIMC Topic: Antipsychotic Agents

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Prediction of remission of pharmacologically treated psychotic depression: A machine learning approach.

Journal of affective disorders Jul 15, 2025
BACKGROUND: The combination of antidepressant and antipsychotic medication is an effective treatment for major depressive disorder with psychotic features ('psychotic depression'). The present study aims to identify sociodemographic and clinical pred...
Remission Induction Psychotic Disorders Treatment Outcome Regression Analysis Drug Therapy, Combination Antipsychotic Agents Proportional Hazards Models Benzodiazepines Sociodemographic Factors Adult Male Depressive Disorder, Major Adolescent Middle Aged Aged, 80 and over Young Adult Female Aged Predictive Learning Models Humans Machine Learning Olanzapine Sertraline Antidepressive Agents Cost of Illness
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Modeling the Determinants of Subjective Well-Being in Schizophrenia.

Schizophrenia bulletin Jul 7, 2025
BACKGROUND: The ultimate goal of successful schizophrenia treatment is not just to alleviate psychotic symptoms, but also to reduce distress and achieve subjective well-being (SWB). We aimed to identify the determinants of SWB and their interrelation...
Humans Schizophrenia Middle Aged Female Antipsychotic Agents Depression Young Adult Obsessive-Compulsive Disorder Adult Cognitive Dysfunction Machine Learning Male Personal Satisfaction
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Principi di farmacodinamica e farmacocinetica nello switch tra antipsicotici: focus su cariprazina.

Rivista di psichiatria Jan 1, 2019
Cariprazina {RGH-188; trans-N- [4- [2- [4- (2,3-diclorofenil) piperazin-1-il] etil] cicloesil] -N_, N_-dimetilurea cloridrato} รจ un antipsicotico atipico di nuova generazione, con un originale profilo farmacodinamico e farmacocinetico. Cariprazina ha...
Drug Substitution Ketoconazole Cytochrome P-450 CYP2D6 Inducers Cytochrome P-450 CYP3A Inducers Schizophrenia Receptor, Serotonin, 5-HT2A Antipsychotic Agents Anhedonia Piperazines Humans Half-Life Drug Interactions Receptor, Serotonin, 5-HT2C Cognition Disorders Time Factors
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Threshold of Dopamine D2/3 Receptor Occupancy for Hyperprolactinemia in Older Patients With Schizophrenia.

The Journal of clinical psychiatry Dec 1, 2016
OBJECTIVE: Although hyperprolactinemia carries a long-term risk of morbidity, the threshold of dopamine D2/3 receptor (D2/3R) occupancy for hyperprolactinemia has not been investigated in older patients with schizophrenia. Data were taken from a posi...
Benzodiazepines Positron-Emission Tomography Prolactin Dopamine Antagonists Receptors, Dopamine D2 Humans Middle Aged Antipsychotic Agents Receptors, Dopamine D3 Schizophrenia Olanzapine Corpus Striatum Risperidone Female Raclopride Aged, 80 and over Hyperprolactinemia Male Aged
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