AIMC Topic: Biomarkers, Tumor

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Serum Level of Matrix Metalloproteinase-9 in Patients with Head and Neck Squamous Cell Carcinoma.

Clinical laboratory
BACKGROUND: Head and neck squamous cell carcinoma (HNSCC) is characterized by the upregulation of a large number of matrix metalloproteinases (MMPs). The aim of the study was to investigate the level of MMP-9 in the sera of HNSCC patients and its rel...

A scoring system based on artificial neural network for predicting 10-year survival in stage II A colon cancer patients after radical surgery.

Oncotarget
Nearly 20% patients with stage II A colon cancer will develop recurrent disease post-operatively. The present study aims to develop a scoring system based on Artificial Neural Network (ANN) model for predicting 10-year survival outcome. The clinical ...

Assessing the association between 25-OH vitamin D levels and ROMA score in a population of obese women.

Journal of biological regulators and homeostatic agents
The “Risk of Malignancy Algorithm” (ROMA) combines the diagnostic power of the CA125 and HE4 markers with menopausal status to predict the risk for developing epithelial ovarian cancer (EOC). The aim of this study was to evaluate the association betw...

Classifying prostate cancer patients based on total prostate-specific antigen and free prostate-specific antigen features by support vector machine.

Journal of cancer research and therapeutics
AIMS OF STUDY: In this work, we enhanced the role of prostate-specific antigen (PSA) test by examining the relation between free PSA (fPSA) and total PSA (tPSA) value and other biological information such as age and volume of prostate. Our primary go...

Evaluation of Machine Learning Algorithm Utilization for Lung Cancer Classification Based on Gene Expression Levels.

Asian Pacific journal of cancer prevention : APJCP
BACKGROUND: Lung cancer remains one of the most common cancers in the world, both in terms of new cases (about 13% of total per year) and deaths (nearly one cancer death in five), because of the high case fatality. Errors in lung cancer type or malig...

HUMAN DNA QUANTIFICATION IN THE STOOLS OF PATIENTS WITH COLORECTAL CANCER.

Arquivos de gastroenterologia
BACKGROUND: Colorectal cancer is one of the main cause of cancer in the world. Colonoscopy is the best screen method, however the compliance is less than 50%. Quantification of human DNA (hDNA) in the feces may be a possible screen non-invasive metho...

In silico discovery of significant pathways in colorectal cancer metastasis using a two-stage optimisation approach.

IET systems biology
Accurate and reliable modelling of protein-protein interaction networks for complex diseases such as colorectal cancer can help better understand mechanism of diseases and potentially discover new drugs. Different machine learning methods such as emp...

[Fragments Woven into a Whole: A New Approach to the Diagnosis of Cancer through Mass Spectrometry and Machine-Learning].

Rinsho byori. The Japanese journal of clinical pathology
Conventionally, a definitive diagnosis of cancer is derived from histopathological diagnostics based on morphological criteria that are difficult to standardize on a quantifiable basis. On the other hand, while molecular tumor markers and blood bioch...