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Blood Platelets

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Regular cold water swimming during winter time affects resting hematological parameters and serum erythropoietin.

Journal of physiology and pharmacology : an official journal of the Polish Physiological Society
Recreational winter swimming in cold sea water evokes body responses to regularly repeated cold water immersion. However, the understanding of adaptive changes is still limited and data regarding very short-term exposure to severe cold stress are sca...

Cooling and Cryopreservation of Equine Platelet-Rich Plasma With Dimethyl Sulfoxide and Trehalose.

Journal of equine veterinary science
Equine platelet-rich plasma (PRP) has been used in horses to repair bone, articular and tendinous lesions, laminitis, and even endometritis. However, platelets have a very limited lifespan, which makes it difficult to prepare and use PRP, except in l...

Machine-Learning Approach for Modeling Myelosuppression Attributed to Nimustine Hydrochloride.

JCO clinical cancer informatics
PURPOSE: A major adverse effect arising from nimustine hydrochloride (ACNU) therapy for brain tumors is myelosuppression. Because its timing and severity vary among individual patients, the ACNU dose level has been adjusted in an empiric manner at in...

The Influence of Mechanical Rubbing on the Dissolution of Blood Clots.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Mechanical rubbing of blood clots is a potential minimally-invasive method for clearing clogged blood vessels. In this work, we investigate the influence of the interaction of the tip of a helical robot with blood clots. This interaction enables the ...

Cell-Like Micromotors.

Accounts of chemical research
In the past decade, versatile micro- and nanosized machines have emerged as active agents for large-scale detoxification, sensing, microfabrication, and many other promising applications. Micromachines have also been envisioned as the next advancemen...

RNA sequencing and swarm intelligence-enhanced classification algorithm development for blood-based disease diagnostics using spliced blood platelet RNA.

Nature protocols
Blood-based diagnostics tests, using individual or panels of biomarkers, may revolutionize disease diagnostics and enable minimally invasive therapy monitoring. However, selection of the most relevant biomarkers from liquid biosources remains an imme...

Reducing demand uncertainty in the platelet supply chain through artificial neural networks and ARIMA models.

Computers in biology and medicine
One of the significant issues in global healthcare systems is improving the supply chain performance and addressing the uncertainties in demand. Blood products, especially platelets, have the most challenging supply chains in the health system given ...

Platelet-rich emboli are associated with von Willebrand factor levels and have poorer revascularization outcomes.

Journal of neurointerventional surgery
BACKGROUND AND AIMS: Platelets and von Willebrand factor (vWF) are key factors in thrombosis and thus are likely key components of acute ischemic stroke (AIS) emboli. We aimed to characterize platelet and vWF levels in AIS emboli and to assess associ...

Enzyme-powered Janus platelet cell robots for active and targeted drug delivery.

Science robotics
Transforming natural cells into functional biocompatible robots capable of active movement is expected to enhance the functions of the cells and revolutionize the development of synthetic micromotors. However, present cell-based micromotor systems co...

Dynamic impact of transfusion ratios on outcomes in severely injured patients: Targeted machine learning analysis of the Pragmatic, Randomized Optimal Platelet and Plasma Ratios randomized clinical trial.

The journal of trauma and acute care surgery
BACKGROUND: Massive transfusion protocols to treat postinjury hemorrhage are based on predefined blood product transfusion ratios followed by goal-directed transfusion based on patient's clinical evolution. However, it remains unclear how these trans...